dermcidin

RefSeq NM_053283

Also Known As:

DCD peptide; DCD protein, human; DCD-1 peptide; DSEP peptide, human; HCAP neoplasm protein, human; SPP peptide; Y-P30 peptide; cachexia-associated protein, human; diffusible survival evasion peptide, human; preproteolysin protein, human; survival-promoting peptide

Networked: 66 relevant articles (2 outcomes, 6 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - dermcidin: 66

Experts

1.	Bank, Sarbashri: 5 articles (01/2019 - 01/2014)
2.	Bhattacharya, Rabindra: 4 articles (09/2014 - 01/2011)
3.	Ghosh, Rajeshwary: 4 articles (09/2014 - 01/2011)
4.	Fenical, William: 3 articles (04/2022 - 10/2014)
5.	Maiti, Smarajit: 3 articles (01/2019 - 07/2014)
6.	Guha, Santanu: 3 articles (01/2016 - 07/2014)
7.	Sinha, A Kumar: 3 articles (09/2014 - 01/2011)
8.	Ross, James A: 3 articles (09/2011 - 09/2007)
9.	Stewart, Grant D: 3 articles (09/2011 - 09/2007)
10.	Huang, Xianzhang: 2 articles (06/2022 - 04/2018)

Related Diseases

1.	Melanoma (Melanoma, Malignant) 04/28/2022 - "Preclinical Development of Seriniquinones as Selective Dermcidin Modulators for the Treatment of Melanoma." 10/01/2016 - "Although melanoma patients have increased serum dermcidin levels, the REPTree classifier showed that levels of dermcidin <2.98 μg/ml predict metastasis in AJCC stage II patients. " 04/28/2022 - "Target deconvolution studies defined the seriniquinones as a new class of melanoma-selective agents that act in part by targeting dermcidin (DCD). " 12/04/2021 - "Isolated from the marine bacteria Serinicoccus sp., seriniquinone (SQ1) has been characterized by its selective activity in melanoma cell lines marked by its modulation of human dermcidin and induction of autophagy and apoptosis. " 01/01/2020 - "We previously demonstrated that in stage II melanoma patients, serum levels of dermcidin (DCD) were associated with metastatic progression. "
2.	Myocardial Ischemia (Ischemic Heart Diseases) 01/01/2014 - "Dermcidin was prepared by electrophoresis using plasma from the subjects with acute ischemic heart disease. " 12/01/2015 - "4,183 Da polypeptide, a fragment of dermcidin protein, may have association with the onset of ischemic heart disease, and may be helpful in the early diagnosis of ACS." 06/01/2017 - "[A novel protein peptide associated with ischemic heart disease: dermcidin]." 12/01/2015 - "To investigate the predictive value of 4,183 Da peptide of dermcidin protein in the early diagnosis and differential diagnosis of ischemic heart disease. "
3.	Neoplasms (Cancer) 10/14/2014 - "This selectivity, along with the ease in medicinal chemical modification, provides a key opportunity to design and evaluate new treatments for those cancers that rely on dermcidin activity. " 06/14/2021 - "To investigate the potential of dermcidin in extramammary Paget's disease, we investigated dermcidin expression in tumors using the immunostaining technique. " 04/08/2011 - "The DCD peptide has been previously shown to be involved in tumorigenesis, to increase tumor survival rate, to improve tumor stress resistance, and to aid growth. " 07/08/2008 - "Dermcidin acts as a survival factor in a variety of cancer cell lines under hypoxia or oxidative stress. " 05/01/2008 - "Recent studies suggest that the Y-P30 subunit of the dermcidin polypeptide offers a survival advantage in such cancer cells. "
4.	Infections 08/01/2019 - "Chemerin and dermcidin may contribute to the protection of infants from infections during infancy. " 12/20/2021 - "The present study aims to investigate the association between dermcidin, salusin-α, and salusin-β in the etiopathology of patients with diabetic foot infection. " 12/20/2021 - "These molecules (dermcidin specifically) can be researched as an adjuvant therapeutic agent in addition to conventional treatments in diabetic foot diabetic foot infections. " 12/20/2021 - "Based on our findings, diabetic foot infection group had significantly lower plasma dermcidin levels and salusin-α and salusin-β levels were significantly higher in the control group. " 12/20/2021 - "Diabetic foot infection group had significantly lower plasma dermcidin levels compared to diabetes only group and control group (P = .000, ANOVA), whereas there was no statistically significant difference between the Group 2 and Group 3 (P = .163, ANOVA). "
5.	Acne Vulgaris 11/01/2018 - "Dermcidin expression is reduced in acne vulgaris. " 11/01/2018 - "Dermcidin was significantly lower in acne vulgaris patients (p < .001). " 11/01/2018 - "Skin dermcidin expression was investigated in 30 patients with moderate-severe acne vulgaris and 15 healthy control subjects using ELISA. " 11/01/2018 - "The present study aimed to investigate dermcidin expression and the effects of low and conventional dose isotretinoin on its expression in acne vulgaris patients. " 01/01/2019 - "Plasma dermcidin levels in acne patients, and the effect of isotretinoin treatment on dermcidin levels."

Related Drugs and Biologics

1.	Proteins (Proteins, Gene)
2.	Peptides (Polypeptides)
3.	Biomarkers (Surrogate Marker)
4.	Vitronectin
5.	dicarboxydine (DCD)
6.	Isotretinoin (Accutane)
7.	Clusterin
8.	CD5 Antigens
9.	Antimicrobial Peptides
10.	Salicylic Acid (2 Hydroxybenzoic Acid)

Related Therapies and Procedures

1.	Catheters
2.	Therapeutics
3.	Ligation
4.	Oral Administration