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bacopaside II

isolated from Bacopa monniera Wettst; structure in first source

Also Known As:

3-O-alpha-L-arabinofuranosyl-(1-2)-(beta-D-glucopyranosyl (1-3))-beta-D-glucopyranosyl pseudo-jujubogenin

Networked: 6 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Carbohydrates: 22023
- Glycosides: 2119
  - Saponins: 2867
    - bacopaside II: 6
Organic Chemicals: 133
- Hydrocarbons: 1713
  - Terpenes: 1461
    - Triterpenes: 2493
      - bacopaside II: 6

Experts

1.	Hardingham, Jennifer E: 3 articles (01/2019 - 02/2018)
2.	Pei, Jinxin V: 3 articles (01/2019 - 02/2018)
3.	Smith, Eric: 3 articles (01/2019 - 02/2018)
4.	Yool, Andrea J: 3 articles (01/2019 - 02/2018)
5.	Palethorpe, Helen M: 2 articles (07/2018 - 02/2018)
6.	Price, Timothy J: 2 articles (07/2018 - 02/2018)
7.	Tomita, Yoko: 2 articles (07/2018 - 02/2018)
8.	Townsend, Amanda R: 2 articles (07/2018 - 02/2018)
9.	Young, Joanne P: 2 articles (07/2018 - 02/2018)
10.	Dasgupta, Debjani: 1 article (01/2021)

Related Diseases

1.	Colonic Neoplasms (Colon Cancer) 07/21/2018 - "The aim of this study was to further elucidate the anti-tumour potential of bacopaside II in colon cancer cells. " 07/21/2018 - "These results are the first to show that bacopaside II inhibits colon cancer cell growth by inducing cell cycle arrest and apoptosis." 07/21/2018 - "The Purified Extract from the Medicinal Plant Bacopa monnieri, Bacopaside II, Inhibits Growth of Colon Cancer Cells In Vitro by Inducing Cell Cycle Arrest and Apoptosis." 01/01/2019 - "Combined pharmacological administration of AQP1 ion channel blocker AqB011 and water channel blocker Bacopaside II amplifies inhibition of colon cancer cell migration."
2.	Alzheimer Disease (Alzheimer's Disease) 08/01/2023 - "Investigating MARK4 inhibitory potential of Bacopaside II: Targeting Alzheimer's disease." 01/01/2021 - "We show that compounds such as bacopaside II, bacopaside XII, and nicotine showed optimal binding features with the R2 repeat domain of hyperphosphorylated tau protein for further consideration in the context of Alzheimer's disease (AD)."
3.	Wounds and Injuries (Trauma) 02/26/2018 - "The effect of bacopaside II on viability, apoptosis, migration and tubulogenesis was assessed by a proliferation assay, annexin-V/propidium iodide flow cytometry, the scratch wound assay and endothelial tube-formation, respectively. "
4.	Breast Neoplasms (Breast Cancer) 06/01/2010 - "The remaining two compounds, bacopaside II (2) and bacopasaponin C (4) were found to be much less potent compared with 1 and 3. 1 and 3 significantly inhibited human breast cancer cell line MDA-MB-231 adhesion, migration and Matrigel invasion in vitro at the concentration of 50 micromol/L. "

Related Drugs and Biologics

1.	Aquaporins (Water Channels)
2.	Annexin A5
3.	tau Proteins (tau Protein)
4.	Propidium (Propidium Iodide)
5.	Nicotine
6.	Ion Channels (Ion Channel)
7.	bacopasaponin C
8.	matrigel