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arjunic acid

from Terminalia arjuna; structure in first source

Networked: 6 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Terpenes: 1461
    - Triterpenes: 2493
      - arjunic acid: 6

Experts

1.	Khanum, Farhath: 2 articles (02/2020 - 01/2019)
2.	Fathima, Asra: 1 article (02/2020)
3.	P, Bhuvanesh Kumar: 1 article (02/2020)
4.	T, Anand: 1 article (02/2020)
5.	T, Mohan Manu: 1 article (02/2020)
6.	Anand, T: 1 article (01/2019)
7.	Kumar, P Bhuvanesh: 1 article (01/2019)
8.	Manu, T Mohan: 1 article (01/2019)
9.	Pandareesh, M D: 1 article (01/2019)
10.	Baek, Nam-In: 1 article (04/2016)

Related Diseases

1.	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 04/01/2016 - "Thus, in the present study, the molecular antitumor mechanism of arjunic acid was examined in A549 and H460 non-small cell lung cancer (NSCLC) cells. " 04/01/2016 - "c-Jun N-terminal Kinase-Dependent Endoplasmic Reticulum Stress Pathway is Critically Involved in Arjunic Acid Induced Apoptosis in Non-Small Cell Lung Cancer Cells."
2.	Neoplasms (Cancer) 11/01/2007 - "Out of the four compounds, arjunic acid (1) was significantly active against the human oral (KB), ovarian (PA 1) and liver (HepG-2 & WRL-68) cancer cell lines. " 10/17/2023 - "luteolin, β-sitosterol and arjunic acid as potent anti-cancer agents and can be extended with in-vitro and in-vivo experiments to validate the in-silico results, thus establishing lead phytochemicals in multi-targeted colorectal cancer therapies with minimal side effects."
3.	Metabolic Syndrome (Dysmetabolic Syndrome X) 02/01/2020 - "Overall, our results suggest that arjungenin and arjunic acid acts as an FXR agonist and may be useful for rational therapeutic strategies as a novel drug to treat cholesterol mediated metabolic syndrome and insulin resistance."
4.	Colorectal Neoplasms (Colorectal Cancer) 10/17/2023 - "luteolin, β-sitosterol and arjunic acid as potent anti-cancer agents and can be extended with in-vitro and in-vivo experiments to validate the in-silico results, thus establishing lead phytochemicals in multi-targeted colorectal cancer therapies with minimal side effects."
5.	Liver Neoplasms (Liver Cancer) 11/01/2007 - "2-O-Palmitoyl arjunic acid (6) showed two times more activity, while 2, 3-di-O-acetyl-, 2-O-p-anisoyl-, 2, 3-di-O-benzoyl- and 2, 3-di-O-p-nitrobenzoyl arjunic acid (7 - 10) showed 1.7 - 2.3 times less activity than the cytotoxic drug vinblastine against the liver cancer cell lines HepG-2 and WRL-68 respectively."

Related Drugs and Biologics

1.	Phytochemicals
2.	JNK Mitogen-Activated Protein Kinases
3.	Luteolin
4.	Free Radical Scavengers
5.	Vinblastine (Vinblastine Sulfate)
6.	Hydrogen Peroxide (Hydroperoxide)
7.	Cholesterol
8.	Ascorbic Acid (Vitamin C)
9.	Antioxidants
10.	gamma-sitosterol (beta-sitosterol)

Related Therapies and Procedures

1.	Therapeutics