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1,2-benzisoxazole

structure in first source

Networked: 3 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Isoxazoles: 155
      - 1,2-benzisoxazole: 3

Experts

1.	Uto, Yoshikazu: 1 article (01/2016)
2.	Anusha, Sebastian: 1 article (09/2015)
3.	Ashwini, Nanjundaswamy: 1 article (09/2015)
4.	Basappa,: 1 article (09/2015)
5.	Bender, Andreas: 1 article (09/2015)
6.	Fuchs, Julian E: 1 article (09/2015)
7.	Garg, Manoj: 1 article (09/2015)
8.	Kanojia, Deepika: 1 article (09/2015)
9.	Koeffler, H Phillip: 1 article (09/2015)
10.	Madan, Vikas: 1 article (09/2015)

Related Diseases

1.	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 09/15/2015 - "Synthesis of 1,2-benzisoxazole tethered 1,2,3-triazoles that exhibit anticancer activity in acute myeloid leukemia cell lines by inhibiting histone deacetylases, and inducing p21 and tubulin acetylation." 09/15/2015 - "In the present study, we attached a 1,2,3-triazole moiety to the third position of a 1,2-benzisoxazole heterocycle via copper(I)-catalyzed azide-alkyne cycloaddition (CuAAC) with various alkynes and established for the title compounds significant antiproliferative effect against human acute myeloid leukemia (AML) cells. "
2.	Shock 10/19/2006 - "In a series of experiments covering the temperature range 1190-1350 K, a plethora of fragmentation products appear in the post shock samples of 1,2-benzisoxazole. " 10/19/2006 - "Isomerization and decomposition of 1,2-benzisoxazole were studied behind reflected shock waves in a pressurized driver, single-pulse shock tube. "
3.	Parkinson Disease (Parkinson's Disease) 01/01/2016 - "1,2-Benzisoxazole was successfully employed in the discovery and development of zonisamide for the treatment of epilepsy and Parkinson's disease. "
4.	Epilepsy (Aura) 01/01/2016 - "1,2-Benzisoxazole was successfully employed in the discovery and development of zonisamide for the treatment of epilepsy and Parkinson's disease. "

Related Drugs and Biologics

1.	Copper
2.	Azides
3.	Alkynes (Acetylenes)
4.	Tubulin
5.	Histone Deacetylases (Histone Deacetylase)
6.	Zonisamide (Zonegran)