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P.polypeptide

a tumor-associated antigen; has been sequenced

Networked: 5 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Biological Factors: 2472
- Antigens: 143924
  - Neoplasm Antigens: 6217
    - P.polypeptide: 5
Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - P.polypeptide: 5

Experts

1.	Leitner, W W: 1 article (11/2001)
2.	Restifo, N P: 1 article (11/2001)
3.	Robbins, P F: 1 article (11/2001)
4.	Rosenberg, S A: 1 article (11/2001)
5.	Touloukian, C E: 1 article (11/2001)

Related Diseases

1.	Infections 01/01/1986 - "Several ts mutants were recovered from "late" passages of Pi, and from an accidental infection, a ts mutant with an altered P polypeptide. " 03/01/1992 - "For detailed analysis of the role of each P protein and of the functional domains on each P polypeptide, we expressed individual P proteins in cultured insect cells after infection with recombinant baculoviruses. "
2.	Coinfection 08/01/1981 - "This recovery was also shown by sequential synthesis of HVJ cl.14-derived P protein (P77K) following the earlier synthesis of HVJo-derived P polypeptide (P79K) in the mixed infection at 39 degrees C. "
3.	Prader-Willi Syndrome (Syndrome, Prader-Willi) 11/15/2001 - "To identify novel, tumor-specific target antigens for vaccine development, we studied immune responses to P.polypeptide, an M(r) 110,000 integral melanosomal membrane protein associated with the Prader-Willi syndrome. "
4.	Neoplasms (Cancer) 11/15/2001 - "Mining the melanosome for tumor vaccine targets: P.polypeptide is a novel tumor-associated antigen." 11/15/2001 - "To identify novel, tumor-specific target antigens for vaccine development, we studied immune responses to P.polypeptide, an M(r) 110,000 integral melanosomal membrane protein associated with the Prader-Willi syndrome. "
5.	Melanoma (Melanoma, Malignant) 11/15/2001 - "Together with expressed sequence tag (EST) and serial analyses of gene expression (SAGE) library analyses, reverse transcription-PCR and Northern blotting verified that P.polypeptide expression was limited to melanoma and melanocytes. "

Related Drugs and Biologics

1.	Proteins (Proteins, Gene)
2.	Cancer Vaccines
3.	Vaccines
4.	RNA (Ribonucleic Acid)
5.	Membrane Proteins (Integral Membrane Proteins)
6.	Antigens