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heterogeneous nuclear ribonucleoprotein A2-B1

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Also Known As:

HNRPA2B1 protein, human; Hnrpa2b1 protein, mouse; heterogeneous nuclear ribonucleoprotein A2-B1, human; heterogeneous nuclear ribonucleoprotein A2-B1, mouse; hnRNP A2; hnRNP A2 protein; hnRNP B1

Networked: 104 relevant articles (2 outcomes, 21 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Sueoka, Eisaburo: 6 articles (11/2008 - 06/2002)
2.	Kamma, H: 6 articles (08/2003 - 04/2000)
3.	Kamma, Hiroshi: 5 articles (09/2005 - 11/2002)
4.	Satoh, H: 5 articles (05/2003 - 04/2000)
5.	Xu, Dan: 4 articles (01/2014 - 04/2004)
6.	Li, Qi-Fu: 4 articles (07/2011 - 07/2008)
7.	Mulshine, James L: 4 articles (09/2010 - 03/2002)
8.	Sueoka, Naoko: 4 articles (08/2005 - 06/2002)
9.	Li, Weimin: 3 articles (01/2014 - 04/2004)
10.	Carson, John H: 3 articles (01/2013 - 04/2005)

Related Diseases

1.	Lung Neoplasms (Lung Cancer) 10/20/2006 - "The aim of this study is to investigate the expression of hnRNP B1 in exfoliative cells in the sputum of patients with lung cancer and its sensitivity and specificity in diagnosis of lung cancer. " 05/01/2003 - "This study examined the immunohistochemical expression of hnRNP B1 in archived sections of resected lung cancers and compared the patterns of expression with those seen in similar archived sections of non-neoplastic lung. " 03/01/2002 - "The authors have outlined how the overexpression of hnRNP A2/B1 was associated significantly with the eventual development of lung cancer, as corroborated by several independent studies. " 09/15/2010 - "hnRNP A2/B1 modulates epithelial-mesenchymal transition in lung cancer cell lines." 01/01/2010 - "The altered expression pattern of hnRNP A2/B1 and/or splicing variant B1 alone in human lung cancer and their potential to serve as molecular markers for early diagnosis remain issues of intense investigation. "
2.	Neoplasms (Cancer) 09/01/2015 - "Nanoparticle-conjugated aptamer targeting hnRNP A2/B1 can recognize multiple tumor cells and inhibit their proliferation." 04/01/2014 - "We showed previously that splicing factors SRSF1, SRSF6, and hnRNP A2/B1 are up-regulated in several cancers and can act as oncogenes when up-regulated. " 02/01/2011 - "The positive rate and immunohistochemistry score of hnRNP A2/B1 in tumor tissue were significantly higher than that in normal tissue (P < 0.01). " 02/01/2011 - "HnRNP A2/B1 was expressed predominantly in the nuclei of tumor cells. " 01/01/2011 - "The colocalization of hnRNP-A2/B1 with c-myc, c-fos, p53, and Rb was translocated from the nucleolus to the cytoplasm during the differentiation of tumor cells. "
3.	Metaplasia 07/01/1998 - "By analyzing 1078 available biopsy specimens from 147 individuals at baseline and 68 individuals who completed the intervention, we frequently detected overexpression of hnRNP A2/B1 in normal and abnormal bronchial epithelium (i.e., in 41% of normal and 37% of squamous metaplasia samples). " 01/01/2001 - "Cytological atypia, bronchial metaplasia, protein (hnRNP A2/B1) overexpression, ras oncogene activation and tumour-suppressor gene deletion, genomic instability (loss of heterozygosity, microsatellite alterations), abnormal methylation, helical CT detection of atypical adenomatous hyperplasia and fluorescent bronchoscopic detection of angiogenic squamous dysplasia offer great promise for molecular diagnosis of lung cancer far in advance of clinical presentation. "
4.	Hyperplasia 04/01/2003 - "In the case of adenocarcinoma, we investigated the utility of hnRNP B1 for both detection of early adenocarcinoma and discrimination of non-invasive lesion, atypical adenomatous hyperplasia (AAH) from adenocarcinoma. " 01/01/2001 - "Cytological atypia, bronchial metaplasia, protein (hnRNP A2/B1) overexpression, ras oncogene activation and tumour-suppressor gene deletion, genomic instability (loss of heterozygosity, microsatellite alterations), abnormal methylation, helical CT detection of atypical adenomatous hyperplasia and fluorescent bronchoscopic detection of angiogenic squamous dysplasia offer great promise for molecular diagnosis of lung cancer far in advance of clinical presentation. "
5.	Genomic Instability 01/01/2001 - "Cytological atypia, bronchial metaplasia, protein (hnRNP A2/B1) overexpression, ras oncogene activation and tumour-suppressor gene deletion, genomic instability (loss of heterozygosity, microsatellite alterations), abnormal methylation, helical CT detection of atypical adenomatous hyperplasia and fluorescent bronchoscopic detection of angiogenic squamous dysplasia offer great promise for molecular diagnosis of lung cancer far in advance of clinical presentation. "

Related Drugs and Biologics

1.	heterogeneous nuclear ribonucleoprotein A2-B1
2.	Heterogeneous-Nuclear Ribonucleoproteins (Informatin)
3.	Carbon Monoxide
4.	Complementary DNA (cDNA)
5.	Messenger RNA (mRNA)
6.	Proteins (Proteins, Gene)
7.	Osteopontin
8.	Cadherins (E-Cadherin)
9.	Ribonucleoproteins
10.	prohibitin

Related Therapies and Procedures

1.	Drug Therapy (Chemotherapy)