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5,10- dihydroxy- 2,2- dimethylpyrano(3,2- b)xanthen- 6(2H)- one

structure in first source

Also Known As:

6-deoxyjacareubin

Networked: 1 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrans: 130
    - 5,10-dihydroxy-2,2-dimethylpyrano(3,2-b)xanthen-6(2H)-one: 1
- Fused-Ring Heterocyclic Compounds
  - 3-Ring Heterocyclic Compounds
    - Xanthenes: 65
      - 5,10-dihydroxy-2,2-dimethylpyrano(3,2-b)xanthen-6(2H)-one: 1

Experts

1.	Hoshino, Tomonori: 1 article (02/2021)
2.	Matsuzawa, Shu-Ichi: 1 article (02/2021)
3.	Takahashi, Ryosuke: 1 article (02/2021)

Related Diseases

1.	Disease Progression 02/01/2021 - "Administration of 6-deoxyjacareubin to this familial ALS model significantly attenuated disease progression and improved locomotor dysfunction. "
2.	Hypoxia (Hypoxemia) 02/01/2021 - "We hypothesized that the modulation of hypoxia signaling by 6-deoxyjacareubin might protect motor neurons in ALS. " 02/01/2021 - "We previously screened small-molecule compounds that inhibit hypoxia-induced cell death and identified 6-deoxyjacareubin. " 02/01/2021 - "6-Deoxyjacareubin, a natural compound preventing hypoxia-induced cell death, ameliorates neurodegeneration in a mouse model of familial amyotrophic lateral sclerosis."
3.	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 02/01/2021 - "6-Deoxyjacareubin, a natural compound preventing hypoxia-induced cell death, ameliorates neurodegeneration in a mouse model of familial amyotrophic lateral sclerosis."