GH Regulated TBC Protein-1

Grtp1gene is regulated by growth hormone; orthologs from human, mouse, rat & Drosophila; contains the TBC signature motif of GTPase activator proteins of Rab-like small GTPases; Grtp1 is expressed at highest levels in testes, with lesser abundance in intestine, kidney, lung, and liver, in the testis, expression of Grtp1 significantly increases post-pubertally; Grtp1 was localized to mouse proximal chromosome 8; Orthologs of this protein are present in human, mouse, rat, and drosophila suggesting that GRTP1 has an important biological role(s). GenBank AF329833 (mouse)

Also Known As:

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Charette, Laci: 1 article (11/2015)
2.	Darie, Costel C: 1 article (11/2015)
3.	Ngounou Wetie, Armand G: 1 article (11/2015)
4.	Ryan, Jeanne P: 1 article (11/2015)
5.	Woods, Alisa G: 1 article (11/2015)
6.	Wormwood, Kelly L: 1 article (11/2015)

Related Diseases

1.

T-Cell Lymphoma (Lymphoma, T Cell) 11/01/2015 - "Increased expression of proto-oncogene Frequently rearranged in advanced T-cell lymphomas 1 (FRAT1), Kinesin family member 14, Integrin alpha6 subunit, growth hormone regulated TBC protein 1, parotid secretory protein, Prolactin-inducible protein precursor, Mucin-16, Ca binding protein migration inhibitory factor-related protein 14 (MRP14) was observed in individuals with ASD. "

Related Drugs and Biologics

1.	Integrin alpha6
2.	CA-125 Antigen (CA 125 Antigen)
3.	Kinesins
4.	Proteins (Proteins, Gene)
5.	Prolactin
6.	Carrier Proteins (Binding Protein)