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AM132

structure in first source

Also Known As:

AM-132

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Indoles: 200
      - AM132: 2
Organic Chemicals: 133
- Ketones: 2618
  - Propiophenones: 1
    - AM132: 2

Experts

1.	Bekenstein, Uriya: 1 article (01/2017)
2.	Bennett, Estelle R: 1 article (01/2017)
3.	Friedson, Lyndon: 1 article (01/2017)
4.	Greenberg, David S: 1 article (01/2017)
5.	Hanin, Geula: 1 article (01/2017)
6.	Mishra, Nibha: 1 article (01/2017)
7.	Soreq, Hermona: 1 article (01/2017)
8.	Volovich, Meshi: 1 article (01/2017)
9.	Arioka, H: 1 article (07/2001)
10.	Fukumoto, H: 1 article (07/2001)

Related Diseases

1.	Lewis Lung Carcinoma 07/01/2001 - "To profile the antitumor effect of AM compounds, the in vivo antitumor effect of AM-132 was evaluated against cytokine-secreting Lewis lung carcinoma (LLC). "
2.	Neoplasms (Cancer) 07/01/2001 - "Tumor-bearing mice were treated with intravenous AM-132 using three different treatment schedules. " 07/01/2001 - "These results suggest a combined effect of AM-132 and cytokines on the blood supply to tumors." 07/01/2001 - "In particular, LLC tumors expressing IL-6 were markedly reduced by AM-132 treatment, and showed coloring of the tumor surface and unusual hemorrhagic necrosis. " 07/01/2001 - "LLC tumors expressing tumor necrosis factor-alpha (TNF-alpha), granulocyte macrophage colony-stimulating factor (GM-CSF), or interleukin (IL)-6 were very sensitive to AM-132. "
3.	Necrosis 07/01/2001 - "In particular, LLC tumors expressing IL-6 were markedly reduced by AM-132 treatment, and showed coloring of the tumor surface and unusual hemorrhagic necrosis. "
4.	Ataxia (Dyssynergia) 01/01/2017 - "In neuromuscular junctions, AM132 co-elevated the nicotinic acetylcholine receptor and AChE, re-balancing neurotransmission and reaching mild muscle incoordination. "

Related Drugs and Biologics

1.	Cytokines
2.	Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)
3.	Interleukin-6 (Interleukin 6)
4.	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
5.	Nicotinic Receptors (Nicotinic Acetylcholine Receptor)
6.	Interleukins