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pramanicin

structure in first source

Networked: 5 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amides: 2428
  - Lactams: 2198
    - pramanicin: 5
- Ethers: 242
  - Cyclic Ethers: 12
    - Epoxy Compounds: 689
      - pramanicin: 5
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Lactams: 2198
    - pramanicin: 5

Experts

1.	Gao, Ying: 1 article (01/2020)
2.	Guo, Zhiyong: 1 article (01/2020)
3.	Kurtán, Tibor: 1 article (01/2020)
4.	Liu, Zhen: 1 article (01/2020)
5.	Mándi, Attila: 1 article (01/2020)
6.	Proksch, Peter: 1 article (01/2020)
7.	Schmitt, Laura: 1 article (01/2020)
8.	Stuhldreier, Fabian: 1 article (01/2020)
9.	Wesselborg, Sebastian: 1 article (01/2020)
10.	Zou, Kun: 1 article (01/2020)

Related Diseases

1.	Leukemia 05/01/2005 - "In the present study, we showed that pramanicin induced apoptosis in Jurkat T leukemia cells in a dose- and time-dependent manner. " 05/01/2005 - "These results suggest pramanicin as a potential apoptosis-inducing small molecule, which acts through a well-defined JNK- and p38-dependent apoptosis signalling pathway in Jurkat T leukemia cells." 01/01/2020 - "Pramanicin A (1) showed strong cytotoxicity against human lymphoma (Ramos) and leukemia (Jurkat J16) cells with IC50 values of 4.7 and 4.4 μM, respectively. " 05/01/2005 - "Pramanicin induces apoptosis in Jurkat leukemia cells: a role for JNK, p38 and caspase activation."
2.	Lymphoma (Lymphomas) 01/01/2020 - "Pramanicin A (1) showed strong cytotoxicity against human lymphoma (Ramos) and leukemia (Jurkat J16) cells with IC50 values of 4.7 and 4.4 μM, respectively. "
3.	Colonic Neoplasms (Colon Cancer) 01/01/2013 - "Pramanicin analog induces apoptosis in human colon cancer cells: critical roles for Bcl-2, Bim, and p38 MAPK signaling."
4.	Blister (Bulla) 01/01/2003 - "Pramanicin caused cell injury characterized by plasmalemmal bleb formation, leading to cell death characterized by Trypan blue staining of the nuclei in cultured vascular endothelial cells in a concentration- and time-dependent manner. "
5.	Vascular Ring 03/01/2001 - "Pretreatment of the endothelium-intact vascular rings with L-N(G)-nitro-arginine (100 microM) inhibited the relaxation of PE-precontracted rings induced by 3 microM carbachol or 100 microM pramanicin, suggesting that the generation of nitric oxide (NO) in endothelial cells mediates the slow vascular relaxation induced by pramanicin. "

Related Drugs and Biologics

1.	p38 Mitogen-Activated Protein Kinases
2.	Caspases
3.	Trypan Blue
4.	Nitric Oxide (Nitrogen Monoxide)
5.	Carbachol (Carbastat)
6.	Arginine (L-Arginine)