diallyl tetrasulfide

Also Known As:

diallyltetrasulfide

Networked: 4 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Acyclic Hydrocarbons
    - Alkenes: 265
      - Allyl Compounds: 7
        diallyl tetrasulfide: 4
- Sulfur Compounds: 278
  - Sulfides: 1062
    - diallyl tetrasulfide: 4
Inorganic Chemicals: 9
- Electrolytes: 16106
  - Ions: 7857
    - Anions: 3501
      - Sulfides: 1062
        diallyl tetrasulfide: 4
- Sulfur Compounds: 278
  - Hydrogen Sulfide: 2764
    - Sulfides: 1062
      - diallyl tetrasulfide: 4

Experts

1.	Jacob, Claus: 2 articles (11/2013 - 11/2012)
2.	Montenarh, Mathias: 2 articles (11/2013 - 03/2012)
3.	Abu Asali, Imad: 1 article (11/2013)
4.	Czepukojc, Brigitte: 1 article (11/2013)
5.	Saidu, Nathaniel Edward Bennett: 1 article (11/2013)
6.	Seitz, Berthold: 1 article (11/2013)
7.	Cerella, Claudia: 1 article (11/2012)
8.	Dicato, Mario: 1 article (11/2012)
9.	Diederich, Marc: 1 article (11/2012)
10.	Kelkel, Mareike: 1 article (11/2012)

Related Diseases

1.	Neoplasms (Cancer) 11/01/2013 - "Normal ARPE-19 cells were treated with diallyl tetrasulfide to study their cellular response and the results were compared with those of HCT116 cancer cells. " 11/01/2013 - "We found that diallyl tetrasulfide induced reactive oxygen species (ROS) in normal cells similar to cancer cells in a time (0 to 60min) and dose dependent manner (0 to 50μM). " 03/01/2012 - "Diallyl polysulfanes, such as diallyl trisulfide and diallyl tetrasulfide, are regarded as a group of potential chemopreventive compounds as they have been proven to be effective inhibitors of cancer cells. "
2.	B-Cell Lymphoma (Lymphoma, B Cell) 11/01/2012 - "Here, we provide evidence that c-jun N-terminal kinase, which is activated early in response to diallyl tetrasulfide treatment, mediates multisite phosphorylation and subsequent proteolysis of the anti-apoptotic protein B-cell lymphoma 2. As the latter event occurs concomitantly with the onset of apoptosis and the chemical c-jun N-terminal kinase inhibitor SP600125 not only prevented B-cell lymphoma 2 phosphorylation and proteolysis but also apoptosis following diallyl tetrasulfide treatment, we suggest that these c-jun N-terminal kinase-mediated modulations of B-cell lymphoma 2 represent the missing link connecting early microtubule inactivation to the induction of apoptosis."
3.	Colorectal Neoplasms (Colorectal Cancer) 09/01/2023 - "Garlic-derived extracts and several of its individual constituents, especially organosulfur compounds such as allicin, diallyl sulfide, diallyl disulfide, diallyl trisulfide, diallyl tetrasulfide, allylmethylsulfide, S-allylmercaptocysteine, Z-ajoene, thiacremonone and Se-methyl-L-selenocysteine were found to possess cytotoxic, cytostatic, antiangiogenic and antimetastatic activities in different in vitro and in vivo models of colorectal cancer. "

Related Drugs and Biologics

1.	diallyl trisulfide
2.	Cytostatic Agents
3.	Apoptosis Regulatory Proteins
4.	JNK Mitogen-Activated Protein Kinases
5.	Reactive Oxygen Species (Oxygen Radicals)
6.	Selenocysteine
7.	thiacremonone
8.	pyrazolanthrone
9.	S-allylmercaptocysteine
10.	allyl methyl sulfide