glutamine - phenylpyruvate transaminase

a cysteine conjugate beta-lyase which also carries out transamination of glutamine; without beta-lyase activity use glutamine-pyruvate aminotransferase (EC 2.6.1.15)

Also Known As:

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Cooper, Arthur J L: 2 articles (12/2019 - 11/2019)
2.	Dorai, Bhuvaneswari: 1 article (12/2019)
3.	Dorai, Thambi: 1 article (12/2019)
4.	Grasso, Michael: 1 article (12/2019)
5.	Pinto, John T: 1 article (12/2019)
6.	Asaka, Ryoichi: 1 article (11/2019)
7.	Elgogary, Amira: 1 article (11/2019)
8.	Fu, Jie: 1 article (11/2019)
9.	Hanes, Justin: 1 article (11/2019)
10.	Hoang, Giang: 1 article (11/2019)

Related Diseases

1.	Neoplasms (Cancer) 12/18/2019 - "Immunohistochemical analyses revealed that glutamine transaminase K (GTK) and ω-amidase are present in normal and cancerous human prostate and that expression of these enzymes increases in parallel with aggressiveness of the cancer cells. " 11/01/2019 - "Moreover, genetic suppression of glutamine transaminase K (GTK), a key enzyme of the glutaminase II pathway, leads to the complete inhibition of pancreatic tumorigenesis in vivo unveiling GTK as a new metabolic target for cancer therapy. "
2.	Carcinogenesis 11/01/2019 - "Moreover, genetic suppression of glutamine transaminase K (GTK), a key enzyme of the glutaminase II pathway, leads to the complete inhibition of pancreatic tumorigenesis in vivo unveiling GTK as a new metabolic target for cancer therapy. "
3.	Necrosis 12/01/2003 - "Data showed that in the 2- and 3-day treated groups there was substantial necrosis to the straight portion of the proximal tubules (pars recta or S3 segment), rich in glutamine transaminase K (GTK/beta-lyase). "

Related Drugs and Biologics

1.	Enzymes
2.	Lyases
3.	glutamine-pyruvate aminotransferase
4.	amidase

Related Therapies and Procedures

1.	Therapeutics