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recombinant factor VIII SQ

a recombinant factor VIII product similar to the smallest active factor VIII protein found in plasma-derived factor VIII (p-VIII) concentrates; comprises two polypeptide chains of 80 and 90 kDa and lacks the major part of the heavily glycosylated B-domain i.e. amino acids Gln744 to Ser1637
Also Known As:
ReFacto; antihemophilic factor, human recombinant residues 743-1636 deleted; antihemphilic factor, recombinant human b-domain deleted; b-domain deleted recombinant factor viii; human factor viii, recombinant b-domain deleted; moroctocog alfa; r-VIII SQ
Networked: 50 relevant articles (12 outcomes, 17 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Rendo, Pablo: 4 articles (09/2020 - 10/2015)
2. Korth-Bradley, Joan: 3 articles (09/2020 - 05/2015)
3. Rupon, Jeremy: 3 articles (09/2020 - 01/2018)
4. Santagostino, Elena: 3 articles (05/2020 - 08/2004)
5. Korth-Bradley, Joan M: 3 articles (01/2020 - 10/2015)
6. Roth, D A: 3 articles (09/2010 - 05/2005)
7. Stieltjes, N: 3 articles (07/2007 - 11/2003)
8. Bedrosian, C L: 3 articles (01/2003 - 04/2001)
9. Smith, Lynne: 2 articles (09/2020 - 10/2015)
10. Huard, Francois: 2 articles (01/2020 - 07/2017)

Related Diseases

1. Hemophilia A (Haemophilia)
2. Hemorrhage
3. Prion Diseases (Transmissible Spongiform Encephalopathies)
4. Body Weight (Weight, Body)

Related Drugs and Biologics

1. BAY 94-9027
2. Prothrombin (Factor II)
3. NN1731
4. recombinant FVIIa (rFVIIa)
5. anti-inhibitor coagulant complex
6. Factor VIII (Coagulation Factor VIII)
7. recombinant factor VIII SQ
8. Albumins
9. human F8 protein
10. von Willebrand Factor

Related Therapies and Procedures

1. Therapeutics
2. Self Medication
3. Surgical Instruments (Clip)
4. Intravenous Infusions
5. Aftercare (After-Treatment)