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1,3-difluoroacetone

a metabolite of the pesticide gliftor

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Ketones: 2618
  - Acetone: 1775
    - 1,3-difluoroacetone: 1

Experts

1.	Feldwick, M G: 1 article (01/2001)
2.	Mead, R J: 1 article (01/2001)
3.	Menon, K I: 1 article (01/2001)
4.	Noakes, P S: 1 article (01/2001)

Related Diseases

1.

Body Weight (Weight, Body)

01/01/2001 - "Administration of 1,3-difluoroacetone (100 mg kg(-1) body weight) to rats in vivo resulted in (-)-erythro-fluorocitrate synthesis in the kidney, which was preceded by an elevation in fluoride levels and followed by citrate accumulation. "
01/01/2001 - "However, administration of 4-methylpyrazole (90 mg kg(-1) body weight) to rats 2 hours prior to 1,3-difluoroacetone (100 mg kg(-1) body weight) was ineffective in preventing (-)-erythro-fluorocitrate synthesis and did not diminish fluoride or citrate accumulation in vivo. "

Related Drugs and Biologics

1.	Citric Acid (Citrate)
2.	Fluorides
3.	Fomepizole (Antizol)
4.	fluorocitrate