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RP517

structure in first source

Also Known As:

99Tcm-RP517; RP 517; technetium-99m-RP517

Networked: 1 relevant articles (1 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Organometallic Compounds: 64
  - Organotechnetium Compounds: 1
    - RP517: 1

Experts

1.	Barrett, J A: 1 article (11/2000)
2.	Boerman, O C: 1 article (11/2000)
3.	Brouwers, A H: 1 article (11/2000)
4.	Corstens, F H: 1 article (11/2000)
5.	Edwards, D S: 1 article (11/2000)
6.	Harris, T D: 1 article (11/2000)
7.	Laverman, P: 1 article (11/2000)
8.	Oyen, W J: 1 article (11/2000)

Related Diseases

1.	Abscess 11/01/2000 - "Accumulation of 99Tcm-RP517 in the abscess was visualized as early as 1 h p.i. Due to rapid blood clearance (t1/2 alpha=18+/-0.6 min, t1/2 beta=6.5+/-0.4 h) and high abscess uptake, the abscess-to-muscle ratios increased with time from 7.0+/-2.3 at 1 h p.i. to 44.3+/-4.6 at 20 h p.i. The agent mainly cleared via the hepatobiliary route: 50% of the radiolabel was recovered in the small bowel at 1 h p.i., whereas 85% was found in cecum and sigmoid at 20 h p.i. In conclusion, 99Tcm-RP517 rapidly visualized E. "
2.	Escherichia coli Infections 11/01/2000 - "To study the in vivo behaviour of 99Tcm-RP517, rabbits with Escherichia coli infection were injected intravenously with 99Tcm-RP517. "
3.	Inflammation (Inflammations) 11/01/2000 - "In a search for a rapid and accurate imaging agent for scintigraphic detection of infection and inflammation, an LTB4 receptor antagonist, 99Tcm-RP517, which contains the hydrazino nicotinamide moiety, has been developed recently. "
4.	Infections 11/01/2000 - "In a search for a rapid and accurate imaging agent for scintigraphic detection of infection and inflammation, an LTB4 receptor antagonist, 99Tcm-RP517, which contains the hydrazino nicotinamide moiety, has been developed recently. "

Related Drugs and Biologics

1.	Leukotriene B4 Receptors (Leukotriene B4 Receptor)
2.	hydrazino nicotinamide