HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

CpG ODN 1826

possesses two unmethylated CpG units

Also Known As:

CpG-1826; CpG1826

Networked: 33 relevant articles (4 outcomes, 9 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Nucleic Acids, Nucleotides, and Nucleosides: 1
- Nucleotides: 15763
  - Polynucleotides: 218
    - Oligonucleotides: 5145
      - Oligodeoxyribonucleotides: 2217
        CpG ODN 1826: 33

Experts

1.	Pal, Sukumar: 3 articles (03/2014 - 12/2005)
2.	de la Maza, Luis M: 3 articles (03/2014 - 12/2005)
3.	Krieg, Arthur M: 3 articles (08/2004 - 05/2003)
4.	Chen, Wei: 2 articles (01/2013 - 04/2011)
5.	Qiao, Tiankui: 2 articles (01/2013 - 04/2011)
6.	Yuan, Sujuan: 2 articles (01/2013 - 04/2011)
7.	Peterson, Ellena M: 2 articles (08/2009 - 12/2005)
8.	Bhattacharya-Chatterjee, Malaya: 2 articles (02/2009 - 05/2003)
9.	Chatterjee, Sunil K: 2 articles (02/2009 - 05/2003)
10.	Foon, Kenneth A: 2 articles (02/2009 - 05/2003)

Related Diseases

1.	Lung Neoplasms (Lung Cancer) 01/01/2013 - "This study aimed to define the dose-effect relationship for CpG ODN 1826 in increasing radiosensitivity and its impact on immune function in a mouse model of Lewis lung cancer. " 08/19/2015 - "CpG ODN 1826 enhances radiosensitivity of the human lung cancer cell line A549 in a rat model." 04/01/2011 - "The present study extended this finding to the fractionated radiotherapy of the Lewis lung cancer and assessed the ability of CpG ODN 1826 to increase the immune function of mice and the effect of CpG ODN 1826 on the apoptosis of Lewis lung cancer. " 01/01/2013 - "With the increasing concentration of CpG ODN 1826, its effect became more and more significant, meanwhile, inoculation of Lewis lung cancer cells failed in those CpG ODN-cured mice. "
2.	Infections 03/01/2001 - "Treatment of mice with CpG ODN 1826 (TCCATGACGTTCCTGACGTT, with the CpG dinucleotides underlined) or 1585 (ggGGTCAACGTTGAgggggG, with g representing diester linkages and phosphorothioate linkages being to the right of lowercase letters) in the absence of antigen 1 to 2 days prior to challenge with Plasmodium yoelii sporozoites conferred sterile protection against infection. " 10/01/2007 - "In this study, we have attempted to determine whether the systemic administration of CpG oligodeoxynucleotide (CpG-ODN) 1826 would protect mice against systemic lethal Candida albicans infection. "
3.	Periodontitis 01/01/2021 - "This study evaluated the immune effect of pVAX1-HA2-fimA plus CpG-ODN 1826 as an adjuvant in the SD rat periodontitis models to improve the efficacy of the previously used vaccine. "
4.	Malaria 02/01/2004 - "The adjuvant effect of CpG ODN 1826 was manifested as both significantly improved complete protection from malaria (defined as the absence of detectable erythrocytic form parasites) (P = 0.007, chi square) and reduced parasite burden in infected mice. " 02/01/2004 - "We determined the adjuvant effect of murine CpG ODN 1826 on the immunogenicity and protective efficacy of the Saccharomyces cerevisiae-expressed 19-kDa C-terminal region of merozoite surface protein 1 (yMSP1(19)) of the murine malaria parasite Plasmodium yoelii. " 02/01/2004 - "We found that in C57BL/6 mice, following sporozoite challenge, the degree of protective immunity against malaria induced by yMSP1(19) in a formulation of Montanide ISA 51 (ISA) plus CpG ODN 1826 was similar or superior to that conferred by yMSP1(19) emulsified in complete Freund's adjuvant (CFA/incomplete Freund's adjuvant). "
5.	Inflammation (Inflammations) 01/01/2021 - "These results indicated that CpG-ODN 1826 (30 µg) could be used as an effective and safe mucosal adjuvant for pVAX1-HA2-fimA in SD rats since it could elicit mucosal SIgA responses and modulate COX-2 and RANKL production during weeks 1-8, thereby inhibiting inflammation and decreasing bone loss."

Related Drugs and Biologics

1.	Vaccines
2.	Antigens
3.	Merozoite Surface Protein 1 (MSA1)
4.	Secretory Immunoglobulin A (SIgA)
5.	CPG-oligonucleotide
6.	Oligodeoxyribonucleotides
7.	Docetaxel (Taxotere)
8.	cytosine-phosphorothioate guanine
9.	Membrane Proteins (Integral Membrane Proteins)
10.	mannide monooleate

Related Therapies and Procedures

1.	Radiotherapy
2.	Immunotherapy
3.	Therapeutics
4.	Intraperitoneal Injections
5.	Injections