HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

di-p-toluoyltartaric acid

structure in first source

Also Known As:

di-p-toluoyl-D-tartaric acid

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Carboxylic Acids: 973
  - Hydroxy Acids: 94
    - Sugar Acids: 4
      - Tartrates: 3
        di-p-toluoyltartaric acid: 1
  - Acyclic Acids
    - Dicarboxylic Acids: 108
      - Tartrates: 3
        di-p-toluoyltartaric acid: 1
    - Sugar Acids: 4
      - Tartrates: 3
        di-p-toluoyltartaric acid: 1
Carbohydrates: 22023
- Sugar Acids: 4
  - Tartrates: 3
    - di-p-toluoyltartaric acid: 1

Related Diseases

1.

Overactive Urinary Bladder (Overactive Bladder)

10/01/1996 - "Using di-p-toluoyltartaric acid as a resolving agent, the synthetic (+/-)-3 was resolved into its optically pure forms, (-)- and (+)-3. The (-)-enantiomer (-)-3.HCl (FK584) showed about ten times more potent inhibitory activity on urinary bladder rhythmic contraction in rats (ED30 = 0.18 mg/kg, i.v.) than terodiline (ED30 = 1.9 mg/kg, i.v.), while the (+)-enantiomer (+)-3.HCl showed no inhibitory activity at 1.0 mg/kg i.v. Compound (-)-3.HCl (FK584) has pharmacological properties similar to those of terodiline, as evaluated by in vitro assay and is currently in clinical development for the treatment of overactive detrusor."

Related Drugs and Biologics

1.	4,4-diphenyl-2-cyclopentenylamine
2.	terodiline (TD 758)