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interleukin-4 variant

selectively induces apoptosis in acute lymphoblastic leukemia cells

Also Known As:

interleukin-4, Bay 36-1677

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Intercellular Signaling Peptides and Proteins: 29768
    - Cytokines: 164289
      - Interleukins: 25257
        Interleukin-4: 11979
        interleukin-4 variant: 2
- Peptides: 82426
  - Intercellular Signaling Peptides and Proteins: 29768
    - Cytokines: 164289
      - Interleukins: 25257
        Interleukin-4: 11979
        interleukin-4 variant: 2
Biological Factors: 2472
- Intercellular Signaling Peptides and Proteins: 29768
  - Cytokines: 164289
    - Interleukins: 25257
      - Interleukin-4: 11979
        interleukin-4 variant: 2

Experts

1.	Fuller, Rick: 1 article (10/2007)
2.	Getz, Elise Burmeister: 1 article (10/2007)
3.	Longphre, Malinda: 1 article (10/2007)
4.	Wenzel, Sally: 1 article (10/2007)
5.	Wilbraham, Darren: 1 article (10/2007)
6.	Behm, F G: 1 article (02/2001)
7.	Campana, D: 1 article (02/2001)
8.	Forte, C P: 1 article (02/2001)
9.	Pui, C H: 1 article (02/2001)
10.	Raimondi, S C: 1 article (02/2001)

Related Diseases

1.	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 02/01/2001 - "Interleukin-4 variant (BAY 36-1677) selectively induces apoptosis in acute lymphoblastic leukemia cells."
2.	Inflammation (Inflammations) 10/20/2007 - "Our aim was to assess the therapeutic effect of pitrakinra, an interleukin-4 variant that targets allergic Th2 inflammation by potently inhibiting the binding of interleukin 4 and interleukin 13 to interleukin-4Ralpha receptor complexes. "

Related Drugs and Biologics

1.	Therapeutic Uses
2.	Interleukin-13
3.	Interleukin-4 (Interleukin 4)
4.	pitrakinra