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BKM 872

structure in first source

Also Known As:

BKM-872; c(Arg-Arg-Eac-Ser-DF5F-Oic-Arg); cyclo(arginyl-arginyl-6-aminocaproyl-seryl-pentafluorophenylalanyl-octahydroindole-2-carbonyl-arginyl)

Networked: 1 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Halogenated Hydrocarbons: 42
    - Fluorinated Hydrocarbons: 4
      - Fluorocarbons: 1209
        BKM 872: 1
Polycyclic Compounds: 6
- Macrocyclic Compounds: 15
  - Cyclic Peptides: 530
    - BKM 872: 1
Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - Cyclic Peptides: 530
    - BKM 872: 1

Experts

1.	Kotovych, G: 1 article (06/2000)
2.	Miskolzie, M: 1 article (06/2000)
3.	Stewart, J M: 1 article (06/2000)
4.	Yamamoto, H: 1 article (06/2000)
5.	York, E J: 1 article (06/2000)

Related Diseases

1.

Neoplasms (Cancer)

06/01/2000 - "There is no solution structure for BKM-870 and BKM-872 but a correlation between the primary sequence Arg(terminal)-DArg1-Arg2-long chain aliphatic amino acid and anti-cancer activity is evident."
06/01/2000 - "A detailed NMR study is carried out in acetonitrile/water solutions on three novel cyclic bradykinin antagonist analogues, BKM-824, BKM-870, and BKM-872, to examine their solution structures, and to correlate the structures with bradykinin antagonist and anti-cancer activities. "

Related Drugs and Biologics

1.	Bradykinin Receptor Antagonists
2.	Solutions
3.	BKM 870
4.	acetonitrile
5.	Amino Acids