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(bisindazole)tetrachlororuthenate(III)

structure of indazolium salt in first source

Also Known As:

HInd(RuInd2Cl4); trans-indazollium (bisindazole) tetrachlororuthenate(III)

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Pyrazoles: 61
      - Indazoles: 179
        (bisindazole)tetrachlororuthenate(III): 3
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Indazoles: 179
      - (bisindazole)tetrachlororuthenate(III): 3
Organic Chemicals: 133
- Organometallic Compounds: 64
  - (bisindazole)tetrachlororuthenate(III): 3

Related Diseases

1.	Neoplasms (Cancer) 01/28/1994 - "The interaction of two ruthenium(III) complexes exhibiting high anticancer activity, namely trans-indazolium(bisindazole)tetrachlororuthenate(III) (ru-ind) and trans-imidazolium(bisimidazole)tetrachlororuthenate(III) (ru-im), with human serum apotransferrin has been investigated through spectroscopic and chromatographic techniques with the ultimate goal of preparing adducts with good selectivity for cancer cells. " 01/01/1994 - "The interaction of two ruthenium(III) complexes exhibiting high anticancer activity - namely trans-Indazolium(bisindazole) tetrachlororuthenate(III), Hlnd[RuInd(2)Cl(4)], and trans-Imidazolium (bisimidazole) tetrachlororuthenate(III), Hlm[RuIm(2)Cl(4)], - with human serum apotransferrin has been investigated through spectroscopic and chromatographic techniques with the ultimate goal of preparing adducts with good selectivity for cancer cells due to the fact that tumour cells express high amounts of transferrin receptors on their cell surface. "
2.	Colorectal Neoplasms (Colorectal Cancer) 01/01/1992 - "The antineoplastic activity of the ruthenium complexes trans-imidazolium[tetracholorobisimidazole-ruthenate(III)], HIm(RuIm2Cl4), trans-indazolium-[tetrachlorobis(1H-indazole)ruthenate (III, N2)], HInd [RuInd2Cl4(N2)], and trans-indazolium[tetrachloro-bis(2H-indazole)ruthenate(III,N 1)], HInd[RuInd2Cl4-(N1)] was assessed in acetoxymethylmethylnitrosamine-induced autochthonous colorectal carcinomas of Sprague-Dawley rats. "

Related Drugs and Biologics

1.	Ruthenium
2.	apotransferrin
3.	Transferrin Receptors (Transferrin Receptor)
4.	Indazoles
5.	Antineoplastic Agents (Antineoplastics)