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textilinin

from Pseudonaja textilis textilis; Txln 1 & 2 are isoforms; amino acid sequence known

Also Known As:

Txln 1; Txln 2

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Complex Mixtures: 1906
- Venoms: 4328
  - Snake Venoms: 1139
    - Elapid Venoms: 169
      - textilinin: 3
Biological Factors: 2472
- Biological Toxins: 20
  - Venoms: 4328
    - Snake Venoms: 1139
      - Elapid Venoms: 169
        textilinin: 3

Experts

1.	Lavin, Martin F: 2 articles (08/2022 - 04/2009)
2.	Kijas, Amanda W: 1 article (08/2022)
3.	Lauko, Jan: 1 article (08/2022)
4.	Rowan, Alan E: 1 article (08/2022)
5.	Wang, Zhao: 1 article (08/2022)
6.	Yegappan, Ramanathan: 1 article (08/2022)
7.	Du, Qianyun S: 1 article (04/2009)
8.	Flight, Simone M: 1 article (04/2009)
9.	Gaffney, Patrick J: 1 article (04/2009)
10.	Johnson, Lambro A: 1 article (04/2009)

Related Diseases

1.	Thrombosis (Thrombus) 06/01/2000 - "It is proposed that the kinetic profiles of Txln 1 and 2 for plasmin allow the arrest of haemorrhage without the possible threat of thrombosis." 01/01/2022 - "Herein, a novel rapid wound sealant, composed of two recombinant snake venom proteins, the procoagulant ecarin, to rapidly initiate blood clotting and the antifibrinolytic textilinin, to prevent blood clot breakdown within a synthetic thermoresponsive hydrogel scaffold is developed. "
2.	Wounds and Injuries (Trauma) 01/01/2022 - "Herein, a novel rapid wound sealant, composed of two recombinant snake venom proteins, the procoagulant ecarin, to rapidly initiate blood clotting and the antifibrinolytic textilinin, to prevent blood clot breakdown within a synthetic thermoresponsive hydrogel scaffold is developed. "
3.	Hemorrhage 04/01/2009 - "In a mouse tail-vein bleeding model, intravenous textilinin-1 and aprotinin caused similar decreases in blood loss but time to haemostasis in the textilinin-treated animals was significantly shorter than in aprotinin-treated mice. "

Related Drugs and Biologics

1.	Hydrogels
2.	Snake Venoms (Snake Venom)
3.	Proteins (Proteins, Gene)
4.	Aprotinin (Trasylol)
5.	Fibrinolysin
6.	Antifibrinolytic Agents (Antifibrinolytics)
7.	ecarin