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beta-carboline 9N-methyltransferase

acts on beta-carbolines such as harman, harmine, norharman, and harmol to form 2N,9N-dimethyl beta-carbolinium cations

Also Known As:

betaC-9-MT

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Transferases: 6589
    - One-Carbon Group Transferases
      - Methyltransferases: 5778
        beta-carboline 9N-methyltransferase: 1

Experts

1.	Collins, M A: 1 article (06/2000)
2.	Gearhart, D A: 1 article (06/2000)
3.	Lee, J M: 1 article (06/2000)
4.	Neafsey, E J: 1 article (06/2000)

Related Diseases

1.

Parkinson Disease (Parkinson's Disease)

06/01/2000 - "Likewise, supernatant fraction beta-carboline 9N-methyltransferase activity was similar in the putamen and substantia nigra from Parkinson's disease and control cases. "
06/01/2000 - "Increased beta-carboline 9N-methyltransferase activity in the frontal cortex in Parkinson's disease."
06/01/2000 - "Unexpectedly, supernatant fraction beta-carboline 9N-methyltransferase activity was increased fourfold in Parkinson's disease frontal cortex (P < 0.05), suggesting that beta-carboline N-methylation may play a role in Parkinson's disease."

Related Drugs and Biologics

1.	norharman