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otonecine

structure in first source

Also Known As:

oto-necine

Networked: 1 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Alkaloids: 5398
  - Pyrrolizidine Alkaloids: 290
    - otonecine: 1
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Pyrrolizidine Alkaloids: 290
      - otonecine: 1

Experts

1.	Chou, Ming W: 1 article (05/2008)
2.	Fu, Peter P: 1 article (05/2008)
3.	Xia, Qingsu: 1 article (05/2008)
4.	Yan, Jian: 1 article (05/2008)

Related Diseases

1.

Neoplasms (Cancer)

05/05/2008 - "Our mechanistic studies have determined that metabolism of the retronecine-type (riddelliine, retrorsine, and monocrotaline), heliotridine-type (lasiocarpine), and otonecine-type (clivorine) tumorigenic pyrrolizidine alkaloids in vivo and/or in vitro all generates a common set of 6,7-dihydro-7-hydroxy-1-hydroxymethyl-5H-pyrrolizine (DHP)-derived DNA adducts responsible for tumor induction. "

Related Drugs and Biologics

1.	DNA Adducts
2.	Monocrotaline
3.	Pyrrolizidine Alkaloids
4.	clivorine
5.	retronecine
6.	riddelliine
7.	dehydroretronecine
8.	lasiocarpine
9.	retrorsine (usaramine)