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1,2,3,4,6,7-hexachlorinated naphthalene

accelerates the spermatogenesis in rat

Also Known As:

1,2,3,4,6,7-HxCN; 1,2,3,4,6,7-hexachloronaphthalene; PCN 66

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Polycyclic Aromatic Hydrocarbons: 2020
        Naphthalenes: 18
        1,2,3,4,6,7-hexachlorinated naphthalene: 2
  - Halogenated Hydrocarbons: 42
    - Chlorinated Hydrocarbons: 240
      - 1,2,3,4,6,7-hexachlorinated naphthalene: 2
Polycyclic Compounds: 6
- Polycyclic Aromatic Hydrocarbons: 2020
  - Naphthalenes: 18
    - 1,2,3,4,6,7-hexachlorinated naphthalene: 2

Experts

1.	DeVito, Michael J: 1 article (11/2012)
2.	Fomby, Laurene M: 1 article (11/2012)
3.	Hooth, Michelle J: 1 article (11/2012)
4.	Nyska, Abraham: 1 article (11/2012)
5.	Vallant, Molly: 1 article (11/2012)
6.	Vasconcelos, Daphne Y: 1 article (11/2012)
7.	Walker, Nigel J: 1 article (11/2012)
8.	Hirata, M: 1 article (06/2000)
9.	Inoue, N: 1 article (06/2000)
10.	Makita, Y: 1 article (06/2000)

Related Diseases

1.	Body Weight (Weight, Body) 06/01/2000 - "We treated pregnant rats with 1 microg/kg body weight/day 1,2,3,4,6,7-hexachlorinated naphthalene (1,2,3,4,6,7-HxCN) on days 14-16 of gestation and examined the effects on the reproductive systems of their male offspring at various phases of sexual maturation. "
2.	Atrophy 11/15/2012 - "Dose response modeling of CYP1A1, CYP1A2 and thymic atrophy gave ranges of estimated relative potencies, as compared to TCDD, of 0.0015-0.0072, for PCN 66 and 0.00029-0.00067 for PCN 67. " 11/15/2012 - "Repeated dose toxicity and relative potency of 1,2,3,4,6,7-hexachloronaphthalene (PCN 66) 1,2,3,5,6,7-hexachloronaphthalene (PCN 67) compared to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) for induction of CYP1A1, CYP1A2 and thymic atrophy in female Harlan Sprague-Dawley rats."

Related Drugs and Biologics

1.	1,2,3,4,6,7-hexachlorinated naphthalene
2.	Cytochrome P-450 CYP1A2 (CYP1A2)
3.	Cytochrome P-450 CYP1A1 (CYP1A1)
4.	Polychlorinated Dibenzodioxins (TCDD)
5.	1,2,3,5,6,7-hexachloronaphthalene