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tetramethylrosamine

structure in first source

Also Known As:

rosamine

Networked: 5 relevant articles (1 outcomes, 2 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 3-Ring Heterocyclic Compounds
    - Xanthenes: 65
      - Rhodamines: 466
        tetramethylrosamine: 5
    - tetramethylrosamine: 5

Experts

1.	Burgess, Kevin: 2 articles (01/2014 - 07/2009)
2.	Lee, Hong Boon: 2 articles (01/2014 - 07/2009)
3.	Lim, Siang Hui: 2 articles (01/2014 - 07/2009)
4.	Wu, Liangxing: 2 articles (01/2014 - 07/2009)
5.	Detty, Michael R: 2 articles (12/2005 - 05/2004)
6.	Donnelly, David J: 2 articles (12/2005 - 05/2004)
7.	Gibson, Scott L: 2 articles (12/2005 - 05/2004)
8.	Chung, Lip Yong: 1 article (01/2014)
9.	Kiew, Lik Voon: 1 article (01/2014)
10.	Holt, Jason J: 1 article (12/2005)

Related Diseases

1.	Colorectal Neoplasms (Colorectal Cancer) 01/01/2014 - "A NCI-60 cell lines screen further indicated that rosamine analogs 4 and 5 exhibited potent antiproliferative effects with Log10GI50 = -7 (GI50 = 0.1 µM) and were more effective against a colorectal cancer sub-panel than other cell lines. "
2.	Neoplasms (Cancer) 01/01/2014 - "This present study describes in vitro cytotoxicity of second-generation rosamine analogs, their mode of action, and their in vivo efficacies in a tumor allografted mouse model. " 07/01/2009 - "New cytotoxic rosamine derivatives selectively accumulate in the mitochondria of cancer cells."
3.	Phototoxic Dermatitis (Phototoxicity) 12/01/2005 - "Structure-activity studies of uptake and phototoxicity with heavy-chalcogen analogues of tetramethylrosamine in vitro in chemosensitive and multidrug-resistant cells."
4.	Adenocarcinoma 03/01/2001 - "Drug uptake was determined by measuring accumulation of tetramethylrosamine in multidrug resistant NCI AdrR human adenocarcinoma cells. " 05/15/2004 - "Both the thio and selenoanalogues of tetramethylrosamine were efficient photosensitizers against R3230AC rat mammary adenocarcinoma cells in vitro."
5.	Dehydration (Water Stress) 05/15/2004 - "Thio and seleno analogues of tetramethylrosamine were prepared by the directed-metalation/cyclization of the corresponding N,N-diethyl 2-(3-dimethylaminophenylchalcogeno)-4-dimethylaminobenzamide to the 2,7-bis-(N,N-dimethylamino)-9H-chalcogenoxanthen-9-one followed by the addition of phenylmagnesium bromide, dehydration, and ion exchange to the chloride salt. "

Related Drugs and Biologics

1.	Photosensitizing Agents (Photosensitizers)
2.	Salts
3.	Chlorides
4.	Bromides