glutathione S-transferase Mu 2

prevents the formation of neurotoxic aminochrome and dopachrome by catalyzing the conjugation of dopamine and dopa o-quinone with glutathione

Also Known As:

GSTM2 glutathione transferase; GSTM2 protein, human; GSTM2-2 protein, human; Gstm2 protein, mouse; Gstm2 protein, rat; glutathione S-transferase M2 (muscle) protein, human; glutathione S-transferase Mu 2, human; glutathione S-transferase, mu 2 protein, mouse; glutathione S-transferase, mu 2, rat; glutathione transferase M2-2; gsta4 protein, rat

Networked: 6 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Transferases: 6589
    - Alkyl and Aryl Transferases: 180
      - Glutathione Transferase: 4015
        glutathione S-transferase Mu 2: 6

Experts

1.	Hong, Chen-Tai: 1 article (07/2022)
2.	Liu, Pei-Yu: 1 article (07/2022)
3.	Liu, Yi-Wen: 1 article (07/2022)
4.	Shen, Cheng-Huang: 1 article (07/2022)
5.	Wang, Chi-Hung: 1 article (07/2022)
6.	Wang, Shou-Chieh: 1 article (07/2022)
7.	Wu, Jin-Yi: 1 article (07/2022)
8.	Wu, Sin-Rong: 1 article (07/2022)
9.	Chen, Yinghua: 1 article (01/2022)
10.	Guo, Jiao: 1 article (01/2022)

Related Diseases

1.	Neuroblastoma 04/01/2021 - "Secretion of the enzyme glutathione transferase M2-2 from U373MG cells, used as a cellular model for astrocytes, has been reported, and the enzyme is taken up by neuroblastoma SYSH-S7 cells and provide protection against aminochrome. "
2.	Parkinson Disease (Parkinson's Disease) 03/01/2024 - "In conclusion, based on the hypothesis that the neurodegenerative process of idiopathic Parkinson's disease corresponds to a single-neuron neurodegeneration model, we must search for molecules that increase the expression of the neuroprotective enzymes DT-diaphorase and glutathione transferase M2-2. "
3.	Neoplasms (Cancer) 08/01/2014 - "These genes are RNA-binding motif, single-stranded interacting protein 1 (RBMS1), ribosomal protein L29 (RPL29), glutathione S-transferase mu 2 (GSTM2), C15orf32, Akt3, B cell translocation gene 1 (BTG1), C6orf62, C7orf60, kinesin-associated protein 3 (KIFAP3), FBXO11, AT-rich interactive domain 4A (ARID4A), COPS2, TBPL1\|SLC2A12, TMEM59, SNORD46, glioma tumor suppressor candidate region gene 2 (GLTSCR2), and LRRFIP. "
4.	Glomerulonephritis 01/30/2014 - "Using the anti-glomerular basement membrane antibody-induced glomerulonephritis (anti-GBM-GN) mouse model, we found that increased expression of glutathione S-transferase Mu 2 (GSTM2) was related to reduced renal damage caused by anti-GBM antibodies. "
5.	Glioma (Gliomas) 08/01/2014 - "These genes are RNA-binding motif, single-stranded interacting protein 1 (RBMS1), ribosomal protein L29 (RPL29), glutathione S-transferase mu 2 (GSTM2), C15orf32, Akt3, B cell translocation gene 1 (BTG1), C6orf62, C7orf60, kinesin-associated protein 3 (KIFAP3), FBXO11, AT-rich interactive domain 4A (ARID4A), COPS2, TBPL1\|SLC2A12, TMEM59, SNORD46, glioma tumor suppressor candidate region gene 2 (GLTSCR2), and LRRFIP. "

Related Drugs and Biologics

1.	Enzymes
2.	aminochrome 1 (aminochrome)
3.	Phytochemicals
4.	NAD(P)H Dehydrogenase (Quinone) (Quinone Reductase)
5.	Kinesins
6.	Proteins (Proteins, Gene)
7.	Antibodies
8.	antiglomerular basement membrane antibody
9.	ribosomal protein L29