phenyllactate dehydratase

from Clostridium sporogenes grown anaerobically on L-phenylalanine catalyses the reversible syn-dehydration of (R)-phenyllactate to (E)-cinnamate; structure in first source.

Also Known As:

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Kobayashi, Yuta: 1 article (10/2016)
2.	Masuo, Shunsuke: 1 article (10/2016)
3.	Oinuma, Ken-Ichi: 1 article (10/2016)
4.	Takaya, Naoki: 1 article (10/2016)
5.	Buckel, Wolfgang: 1 article (04/2002)
6.	Dickert, Sandra: 1 article (04/2002)
7.	Pierik, Antonio J: 1 article (04/2002)
8.	Buckel, W: 1 article (06/2000)
9.	Dickert, S: 1 article (06/2000)
10.	Linder, D: 1 article (06/2000)

Related Diseases

1.

Dehydration (Water Stress) 10/01/2016 - "Thereafter, phenyllactate dehydratase encoded by fldABCI genes in Clostridium sporogenes converts the resulting D-PhLA into CA. The phenyllactate dehydratase expressed by fldABCI in the D-PhLA-producing bacterium fermented glucose to CA, but D-PhLA fermentation and phenyllactate dehydration were aerobic and anaerobic processes, respectively, which disrupted high-yield CA fermentation in single batch cultures. " 06/01/2000 - "Phenyllactate dehydratase from Clostridium sporogenes grown anaerobically on L-phenylalanine catalyses the reversible syn-dehydration of (R)-phenyllactate to (E)-cinnamate. " 04/01/2002 - "The heterotrimeric phenyllactate dehydratase from Clostridium sporogenes, FldABC, catalyses the reversible dehydration of (R)-phenyllactate to (E)-cinnamate in two steps: (i) CoA-transfer from the cofactor cinnamoyl-CoA to phenyllactate to yield phenyllactyl-CoA and the product cinnamate mediated by FldA, a (R)-phenyllactate CoA-transferase; followed by (ii) dehydration of phenyllactyl-CoA to cinnamoyl-CoA mediated by heterodimeric FldBC, a phenyllactyl-CoA dehydratase. "

Related Drugs and Biologics

1.	Cinnamates
2.	Transferases
3.	Phenylalanine (L-Phenylalanine)
4.	Hydro-Lyases (Dehydratases)
5.	Glucose (Dextrose)
6.	Coenzyme A (CoA)
7.	12- (4'- azido- 2'- nitrophenoxy)dodecanoyl- coenzyme A
8.	cinnamoyl-coenzyme A (cinnamoyl-CoA)