glucocorticoid receptor alpha

06/01/2004 - "In the first part of this paper, after a brief description of inflammation in ARDS and our model of translational research, we review the two cellular signaling pathways that are central to the regulation of inflammation-the stimulatory NF-alphaB and the inhibitory GRalpha. "
03/28/2005 - "This study was aimed to investigate the relationship between the expression of GRalpha and GRbeta in colonic mucosal cells of patients with UC, the efficacy of GC therapy and the intensity of inflammation. "
03/28/2005 - "There was no significant association between GRalpha/GRbeta expression and the degree of inflammation of UC. "
03/28/2005 - "GRalpha and GRbeta expression in colonic mucosal specimens were investigated by immunohistochemistry, and compared between GC resistant and sensitive groups, and also among various degrees of inflammation. "
01/01/2005 - "We found that exposure of naïve cells to longitudinal plasma samples led to divergent directions in NF-kappaB and GRalpha activation that reflected the severity of systemic inflammation. "

09/01/2004 - "[Study on glucocorticoid receptor alpha and beta in colonic mucosal cell of patients with ulcerative colitis]."
09/01/2004 - "To investigate the relationship of the expression of GRalpha and GRbeta in the colonic mucosal cell of patients with ulcerative colitis to the efficacy of glucocorticoid (GC) therapy and the intensity of inflammation. "
09/01/2004 - "The expression of GRalpha and GRbeta in the colonic mucosal cell of patients with ulcerative colitis may serve as predictors of glucocorticoid response, but cannot be used as the markers of the severity of inflammation."

01/01/2014 - "Inflammatory activation is associated with a reduced glucocorticoid receptor alpha/beta expression ratio in monocytes of inpatients with melancholic major depressive disorder."
04/15/2006 - "Reduced expression of GRalpha mRNA was shown in both bipolar and major depressive disorder patients in a current depressive state as well as in remission. "
04/15/2006 - "Using quantitative reverse transcription polymerase chain reaction (RT-PCR), GRalpha mRNA and GRbeta mRNA were measured in peripheral blood cells of major depressive disorder patients (depressive n = 18; remissive n = 38), bipolar disorder patients (depressive n = 13; remissive n = 35), normal control subjects (n = 31), and first-degree relatives of major depressive (n = 17) and bipolar (n = 15) disorder patients. "

04/01/2007 - "The GRalpha-positive rate of meningiomas was significantly greater than that of normal dura. "
04/01/2007 - "However, GRalpha's expression had no obvious effect on the proliferative activity of meningiomas, so it may not be a major control of this process."
04/01/2007 - "GRalpha is of significance in meningiomas, which are a target tissue for glucocorticoid. "
04/01/2007 - "There were no significant differences in PI and SPF among GRalpha-negative, GRalpha-weak positive and GRalpha-strong positive meningiomas. "
04/01/2007 - "The GRalpha-positive meningiomas included 13 '+', 15 '++', 9 '+++' and 12 '++++'. "

10/01/2010 - "Altered expression of GRalpha and GRbeta in CPA raises their possible role in the pathophysiology of these adrenal tumors, although further studies are needed to elucidate the potential significance of these findings."
07/01/2004 - "In addition, peroxisomal biogenesis factor 7, glucocorticoid receptor-alpha and tumor-associated calcium signal transducer genes decreased three- to eight-fold. "
05/15/2001 - "These results suggest that the relative levels of the glucocorticoid receptor alpha and the glucocorticoid receptor P may play a role in the occurrence of glucocorticoid resistance in tumor cells during the treatment of hematological malignancies with glucocorticoids."