HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

JTT 606

MF is C22-H17-N6-Cl.HCl

Also Known As:

6-(4-chlorophenyl)-1-methyl-4-(3-pyridylmethyl)-4H-2,3,4,5,10b-pentaazabenzo(e)azulene monohydrochloride; JTT-606; JTT606

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Chikazu, D: 1 article (04/2000)
2.	Iwasaka, T: 1 article (04/2000)
3.	Katagiri, M: 1 article (04/2000)
4.	Kawaguchi, H: 1 article (04/2000)
5.	Manabe, N: 1 article (04/2000)
6.	Nakamura, K: 1 article (04/2000)
7.	Shindo, M: 1 article (04/2000)
8.	Takato, T: 1 article (04/2000)

Related Diseases

1.

Bone Resorption

04/01/2000 - "It is speculated that JTT-606 could be a potent agent for the treatment of osteopenic disorders with elevated osteoclastic bone resorption."
04/01/2000 - "In the search for a new class of bone-sparing agents, we have conducted random screening of the domestic chemical library using 45Ca release assay from prelabeled cultured neonatal mouse calvariae and identified a novel synthetic triazolotriazepine JTT-606 as a candidate for a potent inhibitor of bone resorption. "
04/01/2000 - "A novel synthetic triazolotriazepine derivative JTT-606 inhibits bone resorption by down-regulation of action and production of bone resorptive factors."