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DTPA-methotrexate
Also Known As:
111In-DTPA-methotrexate; DTPA-MTX
Networked:
2
relevant articles (
1
outcomes,
2
trials/studies)
Relationship Network
Bio-Agent Context: Research Results
Organic Chemicals: 133
Amines: 4871
Polyamines: 3918
Pentetic Acid: 1751
DTPA-methotrexate: 2
Carboxylic Acids: 973
Acyclic Acids
Acetates: 4994
Pentetic Acid: 1751
DTPA-methotrexate: 2
Heterocyclic Compounds: 198
Fused-Ring Heterocyclic Compounds
2-Ring Heterocyclic Compounds
Pteridines: 147
Pterins: 160
Aminopterin: 248
Methotrexate: 24010
DTPA-methotrexate: 2
Related Diseases
1.
Neoplasms (Cancer)
05/15/1993 - "
Based on the data of this study, antibody-conjugated rhDHFR and radionuclide-labeled DTPA-MTX complexes provide components for an alternative radioimmunotherapeutic approach that can be expected to result in improved tumor tissue ratios of both the targeting moiety and the radionuclide-labeled derivative as compared to current approaches.
"
06/01/1998 - "
Imaging tumor folate receptors using 111In-DTPA-methotrexate.
"
06/01/1998 - "
This study was aimed to develop an 111In labelled DTPA-methotrexate (DTPA-MTX) to image tumor folate receptors in vivo.
"
2.
Acute Erythroblastic Leukemia (Erythroleukemia)
05/15/1993 - "
Human K562 erythroleukemia cells were used to evaluate under in vitro conditions the DHFR-MTX affinity system for the delivery of 111In-labeled DTPA-MTX to pretargeted alpha-transferrin receptor antibody-rhDHFR conjugates (alpha-TFR-DHFR).
"
Related Drugs and Biologics
1.
Radioisotopes (Radionuclides)
2.
DTPA-methotrexate
3.
Folic Acid (Vitamin M)
4.
Transferrin Receptors (Transferrin Receptor)