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OFU 001

structure in first source

Also Known As:

1-(2'-oxopropyl)-5-fluorouracil; OFU001

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrimidines: 510
    - Pyrimidinones: 71
      - Uracil: 1493
        Fluorouracil: 26711
        OFU 001: 1

Experts

1.	Hatta, H: 1 article (02/2001)
2.	Mori, M: 1 article (02/2001)
3.	Nishimoto, S I: 1 article (02/2001)
4.	Shibamoto, Y: 1 article (02/2001)
5.	Zhou, L: 1 article (02/2001)

Related Diseases

1.

Neoplasms (Cancer)

02/01/2001 - "Administration of OFU001 (100-200 mg/kg) to the tumor-bearing mice before a single dose of 15-Gy irradiation produced a mean tumor growth delay of 1-5 days as compared to radiation alone (although the delay was not significant). "
02/01/2001 - "To evaluate in vivo efficacy, OFU001 was administered 30 min before irradiation, and radiation-potentiating effects were investigated by means of a tumor growth delay assay and a 50% tumor control dose (TCD-50) assay. "
02/01/2001 - "Following administration of OFU001 and irradiation at 30 Gy, the average 5-FU levels in the tumor and serum were 179 ng/g and 83 ng/mL, respectively. "

Related Drugs and Biologics

1.	Fluorouracil (Carac)