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PCB 180

C12-H3-Cl7

Also Known As:

2,2',3,4,4',5,5'-heptachlorobiphenyl

Networked: 11 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Benzene Derivatives: 17
        Biphenyl Compounds: 7
        Polychlorinated Biphenyls: 1778
        PCB 180: 11
  - Halogenated Hydrocarbons: 42
    - Chlorinated Hydrocarbons: 240
      - Polychlorinated Biphenyls: 1778
        PCB 180: 11
- Dioxins and Dioxin-like Compounds: 5
  - Polychlorinated Biphenyls: 1778
    - PCB 180: 11

Experts

1.	Håkansson, Helen: 3 articles (01/2019 - 06/2011)
2.	Viluksela, Matti: 3 articles (01/2019 - 06/2011)
3.	Andersson, Patrik L: 2 articles (01/2014 - 06/2011)
4.	Halldin, Krister: 2 articles (01/2014 - 06/2011)
5.	Hamers, Timo: 2 articles (01/2014 - 06/2011)
6.	Hamscher, Gerd: 2 articles (01/2014 - 06/2011)
7.	Heikkinen, Päivi: 2 articles (01/2014 - 06/2011)
8.	Korkalainen, Merja: 2 articles (01/2014 - 06/2011)
9.	Leslie, Heather A: 2 articles (01/2014 - 06/2011)
10.	Roos, Robert: 2 articles (01/2014 - 06/2011)

Related Diseases

1.	Breast Neoplasms (Breast Cancer) 02/15/2001 - "The multivariate relative risk of breast cancer for women in the highest quintile of exposure as compared with women in the lowest quintile was 0.82 for DDE (95% confidence interval [CI]: 0.49-1.37) and 0.84 for total PCBs (95% CI: 0.47-1.52), 0.69 for PCB 118 (95% CI: 0.39-1.22), 0.87 for PCB 138 (95% CI: 0.50-1.50), 0.83 for PCB 153 (95% CI: 0.47-1.48), and 0.98 for PCB 180 (95% CI: 0.55-1.75). " 01/01/2002 - "Using human breast cancer cell lines MCF-7 and MDA-MB-231, the effect on BRCA1 expression of chemicals belonging to different classes of organochlorine chemicals (the pesticide toxaphene, 2,3,7,8-tetrachlorodibenzo-p-dioxin, and three polychlorinated biphenyls [PCB#138, PCB#153 and PCB#180]) was measured by a reporter gene construct carrying 267 bp of the BRCA1 promoter. "
2.	Body Weight (Weight, Body) 01/01/2019 - "Here a non-targeted metabolic profiling of rat offspring exposed in utero and lactationally to total doses of 0, 300 or 1000 mg/kg body weight of ultrapure PCB 180 is reported. " 01/01/2014 - "Using a loading dose/maintenance dose regimen, groups of 5 males and 5 females were given total doses of 0, 3, 10, 30, 100, 300, 1000 or 1700 mg PCB 180/kg body weight by gavage. "
3.	Hearing Loss (Hearing Impairment) 05/01/2014 - "The adjusted odds ratio of hearing impairment was significantly increased comparing the highest quartile (Q4) of detectable PCB range with the reference (below LOD): 5.83 (95% CI: 1.20-28.24) for 2,2',3,3',4,4',5-heptachlorobiphenyl (PCB-170), 7.79(95% CI: 1.81-33.44) for 2,2',3,4,4',5,5'-heptachlorobiphenyl (PCB-180), 7.46 (95% CI: 1.62-34.47) for 2,2',3,4',5,5',6-heptachlorobiphenyl (PCB-187), 8.59 (95% CI: 1.26-58.73) for 2,2',3,3',4,4',5,5'-octachlorobiphenyl (PCB-194), 11.62 (95% CI: 2.20-61.55) for 2,2',3,3',4,4',5,6'-octachlorobiphenyl (PCB-196). "
4.	Prostatitis 07/01/2003 - "Adjusting for age, body mass index, and a history of prostatitis, oxychlordane and PCB 180 were associated with an increased risk of prostate cancer. "
5.	Prostatic Neoplasms (Prostate Cancer) 07/01/2003 - "Adjusting for age, body mass index, and a history of prostatitis, oxychlordane and PCB 180 were associated with an increased risk of prostate cancer. "

Related Drugs and Biologics

1.	Polychlorinated Biphenyls (PCBs)
2.	Dichlorodiphenyl Dichloroethylene (DDE)
3.	2,2',3',4,4',5-hexachlorobiphenyl
4.	2,4,5,2',4',5'-hexachlorobiphenyl
5.	Cytochrome P-450 CYP1A1 (CYP1A1)
6.	Toxaphene
7.	Retinoids
8.	Pesticides
9.	Hexachlorobenzene (HCB)
10.	Enzymes