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OPC 51803

a nonpeptide vasopressin V(2)-agonist; structure in first source

Also Known As:

OPC-51803

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrrolidines: 115
    - OPC 51803: 2
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Benzazepines: 5
      - OPC 51803: 2

Experts

1.	Hirano, Takahiro: 1 article (12/2003)
2.	Itoh, Shuji: 1 article (12/2003)
3.	Kambe, Toshimi: 1 article (12/2003)
4.	Kondo, Kazumi: 1 article (12/2003)
5.	Mori, Toyoki: 1 article (12/2003)
6.	Nakamura, Shigeki: 1 article (12/2003)
7.	Yamamura, Yoshitaka: 1 article (12/2003)
8.	Aoyama, M: 1 article (12/2000)
9.	Hirano, T: 1 article (12/2000)
10.	Kondo, K: 1 article (12/2000)

Related Diseases

1.	Diabetes Insipidus 12/01/2000 - "The data suggest that OPC-51803 is a useful therapeutic drug in the treatment of hypothalamic diabetes insipidus, nocturnal enuresis, and some kinds of urinary incontinence." 12/01/2003 - "We assessed the effects of OPC-51803 ((5R)-2-[1-(2-chloro-4-(1-pyrrolidinyl)benzoyl)-2,3,4,5-tetrahydro-1H-1-benzazepin-5-yl]-N-isopropylacetamide), a nonpeptide vasopressin V(2)-receptor agonist, on micturition frequency in female homozygous Brattleboro rats (strain carries hereditary diabetes insipidus) and aged male Sprague-Dawley rats with polyuria. "
2.	Nocturnal Enuresis (Bedwetting) 12/01/2000 - "The data suggest that OPC-51803 is a useful therapeutic drug in the treatment of hypothalamic diabetes insipidus, nocturnal enuresis, and some kinds of urinary incontinence."
3.	Urinary Incontinence 12/01/2000 - "The data suggest that OPC-51803 is a useful therapeutic drug in the treatment of hypothalamic diabetes insipidus, nocturnal enuresis, and some kinds of urinary incontinence."
4.	Polyuria 12/01/2003 - "We assessed the effects of OPC-51803 ((5R)-2-[1-(2-chloro-4-(1-pyrrolidinyl)benzoyl)-2,3,4,5-tetrahydro-1H-1-benzazepin-5-yl]-N-isopropylacetamide), a nonpeptide vasopressin V(2)-receptor agonist, on micturition frequency in female homozygous Brattleboro rats (strain carries hereditary diabetes insipidus) and aged male Sprague-Dawley rats with polyuria. "

Related Drugs and Biologics

1.	Vasopressins (Vasopressin)