Triggering Receptor Expressed on Myeloid Cells-1

An approximately 230 amino acid membrane glycoprotein characterized by an IMMUNOGLOBULIN V-SET DOMAIN in its N-terminal half. It is expressed by MONOCYTES and NEUTROPHILS in response to INFLAMMATION related to bacterial and fungal infections. It triggers the release of pro-inflammatory CHEMOKINES; CYTOKINES, and expression of cell activation markers and is a critical regulator of SEPTIC SHOCK.

Also Known As:

CD354 Antigen; TREM-1 Protein; Antigen, CD354; TREM 1 Protein; Triggering Receptor Expressed on Myeloid Cells 1

Carbohydrates: 22023
- Glycoconjugates: 1353
  - Glycoproteins: 24834
    - Membrane Glycoproteins: 2252
      - Triggering Receptor Expressed on Myeloid Cells-1: 368
Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Glycoproteins: 24834
    - Membrane Glycoproteins: 2252
      - Triggering Receptor Expressed on Myeloid Cells-1: 368
  - Membrane Proteins: 10078
    - Membrane Glycoproteins: 2252
      - Triggering Receptor Expressed on Myeloid Cells-1: 368
    - Cell Surface Receptors: 2125
      - Immunologic Receptors: 9
        Triggering Receptor Expressed on Myeloid Cells-1: 368

human TREM1 protein

Bio-Agent Context: Research Results