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damage-induced neuronal endopeptidase

a membrane-bound metallopeptidase expressed in response to neuronal damage and activates superoxide scavengers; has been sequenced

Also Known As:

DINE metallopeptidase

Networked: 6 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Hydrolases: 2166
    - Peptide Hydrolases: 23957
      - Metalloproteases: 8276
        Metalloendopeptidases: 70
        damage-induced neuronal endopeptidase: 6
      - Endopeptidases: 633
        Metalloendopeptidases: 70
        damage-induced neuronal endopeptidase: 6

Experts

1.	Kiryu-Seo, Sumiko: 5 articles (07/2020 - 11/2002)
2.	Kiyama, Hiroshi: 5 articles (07/2020 - 11/2002)
3.	Kaneko, Aoi: 2 articles (07/2020 - 01/2017)
4.	Matsumoto, Sakiko: 2 articles (07/2020 - 01/2017)
5.	Kato, Ryuichi: 2 articles (03/2008 - 11/2002)
6.	Nagata, Kenichi: 1 article (03/2008)
7.	Nakagomi, Saya: 1 article (03/2008)
8.	Ogawa, Tokiko: 1 article (03/2008)
9.	Kiryu-Seo, S: 1 article (08/2006)
10.	Kiyama, H: 1 article (08/2006)

Related Diseases

1.	Wounds and Injuries (Trauma) 03/14/2008 - "Among many nerve injury-inducible genes, the gene encoding damage-induced neuronal endopeptidase (DINE) showed most marked expression response to various kinds of nerve injuries in central and peripheral nervous system neurons. " 08/11/2006 - "Damage-induced neuronal endopeptidase mRNA expression is strikingly restricted to neurons, and is remarkably induced in response to various types of neuronal injuries, although its function and substrate remain unknown. " 11/01/2002 - "Damage-induced neuronal endopeptidase (DINE) is a novel metallopeptidase and is expressed in response to various neuronal injuries. "
2.	Optic Nerve Injuries 07/17/2020 - "Correction: Damage-induced neuronal endopeptidase (DINE) enhances axonal regeneration potential of retinal ganglion cells after optic nerve injury." 01/01/2017 - "Damage-induced neuronal endopeptidase (DINE) enhances axonal regeneration potential of retinal ganglion cells after optic nerve injury."
3.	Peripheral Nerve Injuries 11/01/2004 - "Damage-induced neuronal endopeptidase (DINE) is a unique nerve-injury associated molecule, which was recently identified in a peripheral nerve injury model. "
4.	Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome) 11/01/2004 - "Expression of damage-induced neuronal endopeptidase (DINE) mRNA in peri-infarct cortical and thalamic neurons following middle cerebral artery occlusion."
5.	Infarction (Infarctions) 11/01/2004 - "Expression of damage-induced neuronal endopeptidase (DINE) mRNA in peri-infarct cortical and thalamic neurons following middle cerebral artery occlusion."

Related Drugs and Biologics

1.	Messenger RNA (mRNA)
2.	Metalloproteases (Metalloproteinases)