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NQ304

structure in first source

Also Known As:

2-chloro-3-(4-hexylphenyl)-amino-1,4-naphthoquinone; NQ 304; NQ-304

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Polycyclic Aromatic Hydrocarbons: 2020
        Naphthalenes: 18
        Naphthoquinones: 418
        NQ304: 2
- Quinones: 434
  - Naphthoquinones: 418
    - NQ304: 2
Polycyclic Compounds: 6
- Polycyclic Aromatic Hydrocarbons: 2020
  - Naphthalenes: 18
    - Naphthoquinones: 418
      - NQ304: 2

Experts

1.	Kim, Tack-Joong: 1 article (01/2007)
2.	Yun, Yeo-Pyo: 1 article (01/2007)
3.	Hong, J T: 1 article (03/2000)
4.	Kang, W S: 1 article (03/2000)
5.	Lee, H Y: 1 article (03/2000)
6.	Ryu, C K: 1 article (03/2000)
7.	Yoo, H S: 1 article (03/2000)
8.	Yuk, D Y: 1 article (03/2000)
9.	Yun, Y P: 1 article (03/2000)

Related Diseases

1.	Atherosclerosis 01/01/2007 - "These data suggest that the anti-proliferative and cell cycle arresting effects of NQ304 on serum-induced VSMCs may be mediated by AP-1 activation downregulation via the suppression of phosphatidylinositol 3-kinase (PI3K)/Akt and ERK1/2 signaling pathways, and it may contribute to the prevention of atherosclerosis through inhibition of VSMC proliferation."
2.	Thrombosis (Thrombus) 03/01/2000 - "NQ304 was found to inhibit platelet aggregation in human platelets in vitro and in rat ex vivo, and murine pulmonary thrombosis in vivo. "

Related Drugs and Biologics

1.	Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)
2.	Transcription Factor AP-1 (Transcription Factor AP 1)