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maurocalcine

a scorpion toxin that activates calcium release channel; amino acid sequence in first source

Also Known As:

Mca toxin

Networked: 4 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Complex Mixtures: 1906
- Venoms: 4328
  - Arthropod Venoms: 770
    - Scorpion Venoms: 373
      - maurocalcine: 4
Biological Factors: 2472
- Biological Toxins: 20
  - Venoms: 4328
    - Arthropod Venoms: 770
      - Scorpion Venoms: 373
        maurocalcine: 4

Experts

1.	Filatova, Margarita P: 2 articles (05/2021 - 01/2019)
2.	Reissmann, Siegmund: 2 articles (05/2021 - 01/2019)
3.	Aroui, Sonia: 2 articles (12/2015 - 04/2009)
4.	De Waard, Michel: 2 articles (12/2015 - 04/2009)
5.	Kenani, Abderraouf: 2 articles (12/2015 - 04/2009)
6.	Hilger, Ingrid: 1 article (01/2019)
7.	Koroev, Dmitri O: 1 article (01/2019)
8.	Lange, Steffi: 1 article (01/2019)
9.	Schumann, Christina: 1 article (01/2019)
10.	Tansi, Felista L: 1 article (01/2019)

Related Diseases

1.	Neoplasms (Cancer) 04/01/2009 - "On a doxorubicin-sensitive cancer cell line, the maurocalcine-conjugated form appears slightly less efficient than doxorubicin itself. " 01/01/2019 - "Thus, we aimed to validate the tumor cell selectivity of peptides from this new generation, namely fragments mini-crotamine and mini-maurocalcine. " 12/07/2015 - "Our results suggested that a chimera between platinum and a maurocalcine-derived CPP is a highly successful anti-cancer compound that works by targeting the intracellular redox system. " 04/01/2009 - "Maurocalcine as a non toxic drug carrier overcomes doxorubicin resistance in the cancer cell line MDA-MB 231." 05/01/2021 - "CPPs with innate tumor selectivity include azurin, crotamine, maurocalcine, lycosin-I, buffalo cathelicidin, and peptide CB5005. "
2.	Glioblastoma (Glioblastoma Multiforme) 12/07/2015 - "A Novel Platinum-Maurocalcine Conjugate Induces Apoptosis of Human Glioblastoma Cells by Acting through the ROS-ERK/AKT-p53 Pathway."

Related Drugs and Biologics

1.	Peptides (Polypeptides)
2.	crotamine
3.	Cathelicidins
4.	Platinum
5.	Drug Carriers
6.	Doxorubicin (Adriamycin)
7.	Azurin
8.	6-chloro-2-(1-piperazinyl)pyrazine (CPP)