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JWG 2000
inhibitor of polo-like kinase1 (PLK1)
Also Known As:
JWG-2000; JWG2000
Networked:
1
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Nucleic Acids, Nucleotides, and Nucleosides: 1
Nucleotides: 15763
Polynucleotides: 218
Oligonucleotides: 5145
Oligodeoxyribonucleotides: 2217
JWG 2000: 1
Experts
1.
Brendel, M
: 1 article (03/2000)
2.
Elez, R
: 1 article (03/2000)
3.
Giannini, C D
: 1 article (03/2000)
4.
Piiper, A
: 1 article (03/2000)
5.
Zeuzem, S
: 1 article (03/2000)
Related Diseases
1.
Neoplasms (Cancer)
03/16/2000 - "
Among 41 phosphorothioate antisense oligodeoxynucleotides tested, the 20-mer JWG2000 strongly inhibited expression of Plk1 in cultured A549 cells, leading to loss of cell viability, and exhibited anti-tumor activity in nude mice A549 xenograft.
"
Related Drugs and Biologics
1.
Oligodeoxyribonucleotides