TRAPP transport protein particle

a multiprotein complex containing ten subunits (Bet5p, Trs20p, Bet3p, Trs23p, Trs33p, Trs31p, Trs65p, Trs85p, Trs120p and Trs130p); plays a key role in the late stages of endoplasmic reticulum to Golgi traffic; amino acid sequence of subunits in first source

Also Known As:

Networked: 3 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Murph, Mikaela: 1 article (01/2022)
2.	Schvarzstein, Mara: 1 article (01/2022)
3.	Singh, Shaneen: 1 article (01/2022)
4.	Baryshnikova, Anastasia: 1 article (04/2016)
5.	Chu, Jaime: 1 article (04/2016)
6.	Cinaroglu, Ayca: 1 article (04/2016)
7.	DeRossi, Charles: 1 article (04/2016)
8.	Freeze, Hudson H: 1 article (04/2016)
9.	Gao, Ningguo: 1 article (04/2016)
10.	Imrie, Dru: 1 article (04/2016)

Related Diseases

1.	Bardet-Biedl Syndrome (Syndrome, Bardet-Biedl) 01/01/2014 - "Recent studies have identified several key regulators of these processes, including Rab GTPases such as Rab8 and Rab11, the Rab8 guanine nucleotide exchange factor Rabin8, and the transport protein particle (TRAPP) components TRAPPC3, -C9, and -C10, which physically interact with each other and function together with Bardet Biedl syndrome (BBS) proteins in ciliary membrane biogenesis. "
2.	Microcephaly 09/01/2022 - ": AIR, Aurora kinase; ASH, Aspm-SPD-2 Hydin; ASP, Abnormal Spindle Protein; ASPM, Abnormal Spindle-like Microcephaly-associated Protein; CC, coiled-coil; CDK, Cyclin-dependent Kinase; Ce, Caenorhabditis elegans; CEP, Centrosomal Protein; CPAP, centrosomal P4.1-associated protein; D, Drosophila; GAP, GTPase activating protein; GEF, GTPase guanine nucleotide exchange factor; Hs, Homo sapiens/Human; Ig, Immunoglobulin; MAP, Microtubule associated Protein; MSP, Major Sperm Protein; MDP, Major Sperm Domain-Containing Protein; OCRL-1, Golgi endocytic trafficking protein Inositol polyphosphate 5-phosphatase; PAR, abnormal embryonic PARtitioning of the cytosol; PCM, Pericentriolar material; PCMD, pericentriolar matrix deficient; PDZ, PSD95/Dlg-1/zo-1; PLK, Polo like kinase; RMSD, Root Mean Square Deviation; SAS, Spindle assembly abnormal proteins; SPD, Spindle-defective protein; TRAPP, TRAnsport Protein Particle; Xe, Xenopus; ZYG, zygote defective protein."
3.	Fatty Liver 04/15/2016 - "We term the pathological UPR that causes fatty liver disease a "stressed UPR." Here we investigate the mechanism of stressed UPR activation in zebrafish bearing a mutation in thetrappc11gene, which encodes a component of the transport protein particle (TRAPP) complex.trappc11mutants are characterized by secretory pathway defects, reflecting disruption of the TRAPP complex. "

Related Drugs and Biologics

1.	Guanine Nucleotide Exchange Factors (Guanine Nucleotide Exchange Factor)
2.	Proteins (Proteins, Gene)
3.	rab GTP-Binding Proteins
4.	Aurora Kinases
5.	GTPase-Activating Proteins (GTPase-Activating Protein)
6.	GTP Phosphohydrolases (GTPases)
7.	Cyclin-Dependent Kinases (cdk Proteins)
8.	Phosphotransferases (Kinase)
9.	Microtubule-Associated Proteins (Microtubule-Associated Protein 2)
10.	Immunoglobulins (Immunoglobulin)