calcyon

01/01/2019 - "Increased arterial pressure in mice with overexpression of the ADHD candidate gene calcyon in forebrain."
06/01/2011 - "Elevated levels of calcyon are consistently observed in brains from schizophrenic patients, and the calcyon gene is associated with attention-deficit hyperactivity disorder. "
07/10/2007 - "As little is known about the potential role of calcyon in ADHD, animal models may provide important insights into this issue. "
07/10/2007 - "At the genetic level, preliminary evidence supports an association between attention-deficit/hyperactivity disorder (ADHD) and polymorphisms in the calcyon gene. "
12/01/2005 - "These findings support the proposed involvement of the calcyon gene in ADHD and implicate haplotype C1 as containing a risk allele."

09/15/2004 - "Finally, our findings suggest that elevations in the expressions of calcyon and NCS-1 in schizophrenia may have the same underlying cause."
09/15/2004 - "Also, up-regulation of both calcyon and NCS-1 in the cortex of schizophrenia patients can be attributed largely to an enhanced transcription or reduced degradation of their messages. "
09/15/2004 - "Furthermore, schizophrenia-associated alterations in the levels of calcyon and NCS-1 messages were correlated. "
01/01/2015 - "Finally, we propose that balancing NEEP21 and Calcyon expression and/or activity could be important for homeostasis in a variety of signaling pathways, and also lead to a novel therapeutic strategy for disorders like Alzheimer's disease and schizophrenia. "
02/15/2004 - "These results suggest that these two genetic variants in the CALCYON gene do not play a major role in predisposition to either schizophrenia or cocaine dependence in AA or EA subjects. "

02/15/2004 - "These results suggest that these two genetic variants in the CALCYON gene do not play a major role in predisposition to either schizophrenia or cocaine dependence in AA or EA subjects. "
02/15/2004 - "Two single nucleotide polymorphisms (SNPs) at the CALCYON locus were genotyped in 70 AA and 206 EA individuals with schizophrenia and 90 AA and 118 EA individuals with cocaine dependence. "
02/15/2004 - "Our objective was to investigate the relationship between polymorphism of the CALCYON gene and (1) schizophrenia and (2) cocaine dependence in African-American (AA) and European-American (EA) subjects. "
02/15/2004 - "CALCYON gene variation, schizophrenia, and cocaine dependence."
05/25/2010 - "The level of mRNA encoding calcyon (measured by in situ hybridization), one of the dopamine receptor interacting proteins, has been examined in the rat brain in the established animal model used to study the mechanisms of cocaine addiction (cocaine self-administration involving a yoked procedure). "

06/03/2008 - "Gene linkage and association studies have implicated the region of chromosome 10q containing the calcyon locus with attention deficit hyperactivity disorder (ADHD), bipolar disorder, and schizophrenia susceptibility. "
09/14/2012 - "Calcyon, once known for interacting directly with the dopamine D(1) receptor (D(1)DR), is implicated in various neuropsychiatric disorders including schizophrenia, bipolar disorder, and attention deficit hyperactivity disorder. "

01/01/2021 - "Our study provides direct evidence for the causal relationship between the hevin-calcyon interaction and synaptic reorganization after brain injury. "
01/01/2021 - "Hevin-calcyon interaction promotes synaptic reorganization after brain injury."