p97 ATPase

binds DNA unwinding factor; involved in membrane fusion; amino acid sequence in first source

Networked: 5 relevant articles (1 outcomes, 1 trials/studies)

1.	Neoplasms (Cancer) 01/01/2023 - "Conclusion: Compound 6 displayed high binding affinity to p97, great p97 ATPase inhibition, selective cytotoxicity, remarkable anti-tumor effect, and upregulated safety, which improved the clinical potential of p97 inhibitors."
2.	Reperfusion Injury 01/01/2021 - "However, certain studies have drawn opposing conclusions, including the mitigation of ischemia/reperfusion injury via inhibition of VCP/p97 ATPase activity. "
3.	Vesicular Stomatitis 12/02/2015 - "Consistently, administration of compounds targeting p97 ATPase activity was shown to inhibit viral replication and protect mice from vesicular stomatitis virus (VSV) infection. "
4.	Inborn Genetic Diseases (Disease, Hereditary) 07/28/2021 - "IBMPFD/ALS is a genetic disorder caused by a single amino acid mutation on the p97 ATPase, promoting ATPase activity and cofactor dysregulation. "
5.	Lymphoma (Lymphomas) 08/07/2015 - "Finally, abrogation of p97 ATPase activity by its specific inhibitor DBeQ, efficiently decreased proliferation of lymphoma cells. "

1.	Amino Acids
2.	Adenosine Triphosphatases (ATPase)