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3',4'- ethylenedioxyphenyl- 2- palmitoylamino- 3- pyrrolidino- 1- propanol

a glucosylceramide synthase inhibitor

Also Known As:

D-EtDO-P4; EtDO-P4

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amines: 4871
  - Amino Alcohols: 20
    - Propanolamines: 4
      - 3',4'-ethylenedioxyphenyl-2-palmitoylamino-3-pyrrolidino-1-propanol: 2
- Alcohols: 595
  - Amino Alcohols: 20
    - Propanolamines: 4
      - 3',4'-ethylenedioxyphenyl-2-palmitoylamino-3-pyrrolidino-1-propanol: 2
  - Propanols: 3
    - Propanolamines: 4
      - 3',4'-ethylenedioxyphenyl-2-palmitoylamino-3-pyrrolidino-1-propanol: 2
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrrolidines: 115
    - 3',4'-ethylenedioxyphenyl-2-palmitoylamino-3-pyrrolidino-1-propanol: 2

Experts

1.	Domek, Hanna: 1 article (01/2016)
2.	Fedoryszak-Kuśka, Natalia: 1 article (01/2016)
3.	Pacuszka, Tadeusz: 1 article (01/2016)
4.	Panasiewicz, Mirosława: 1 article (01/2016)
5.	Kim, Jung Hoe: 1 article (07/2012)
6.	Kwak, Chan-Yeong: 1 article (07/2012)
7.	Park, Seung-Yeol: 1 article (07/2012)
8.	Shayman, James A: 1 article (07/2012)

Related Diseases

1.	Wounds and Injuries (Trauma) 07/01/2012 - "The effect of EtDO-P4 was examined by MTT assay, FACS, wound assay, western blotting, and RTK array analysis. "
2.	Hepatocellular Carcinoma (Hepatoma) 01/01/2016 - "Glucosylceramide synthase inhibitors D-PDMP and D-EtDO-P4 decrease the GM3 ganglioside level, differ in their effects on insulin receptor autophosphorylation but increase Akt1 kinase phosphorylation in human hepatoma HepG2 cells."

Related Drugs and Biologics

1.	Insulin Receptor
2.	Phosphotransferases (Kinase)
3.	G(M3) Ganglioside
4.	RV 538 (PDMP)
5.	ceramide glucosyltransferase