euxanthone

01/01/2021 - "Euxanthone inhibits traumatic spinal cord injury via anti-oxidative stress and suppression of p38 and PI3K/Akt signaling pathway in a rat model."
01/01/2021 - "Owing to neurite promoting, antioxidant and anti-inflammatory effects of Euxanthone (Eux), the investigation was aimed to probe the neuroprotective efficacy of Eux against traumatic spinal cord injury (t-SCI) in rats and whether Eux can improve neuropathic function in t-SCI. Sprague-Dawley (SD) rats were randomized in - Sham, t-SCI, Eux30, and Eux60 (t-SCI + 30 and 60 mg/kg respectively). "

01/10/2020 - "Further, in vivo data demonstrated that euxanthone repressed tumor growth and promoted apoptosis."
12/01/2018 - "In vivo data also showed that euxanthone suppressed tumor growth and promoted pyroptotic cell death. "
12/01/2018 - "This work aimed to explore whether euxanthone exhibits anti-cancer activities in HCC. "
09/15/2018 - "Euxanthone exerts anti-cancer effects in vitro and in vivo in CRC by targeting CIP2A/PP2A signaling."
08/01/2018 - "In vivo experiments also supported that euxanthone could exert anti-cancer activities without general toxicity. "

08/01/2018 - "Our findings provide preliminary experimental data that support further studies on the potential therapeutic role of euxanthone in ovarian cancer."
01/01/2020 - "Retraction notice to "Autophagy is a pro-survival mechanism in ovarian cancer against the apoptotic effects of euxanthone" [Biomed. "
01/01/2018 - "RETRACTED: Autophagy is a pro-survival mechanism in ovarian cancer against the apoptotic effects of euxanthone."

12/01/2018 - "Euxanthone exhibits anti-proliferative and anti-invasive activities in hepatocellular carcinoma by inducing pyroptosis: preliminary results."
11/01/2021 - "In the current study, we studied the effect of euxanthone (EUX) on obesity-associated liver cancer using a high-fat diet-fed mouse model of diethylnitrosamine (DEN)-provoked hepatocellular carcinoma. "

11/01/2021 - "In the current study, we studied the effect of euxanthone (EUX) on obesity-associated liver cancer using a high-fat diet-fed mouse model of diethylnitrosamine (DEN)-provoked hepatocellular carcinoma. "