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BRU 59-21

structure in first source

Also Known As:

BRU59 21; Tc-99m-2-nitroimidazole; technetium Tc 99m 2-nitroimidazole

Networked: 2 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Imidazoles: 150
      - BRU 59-21: 2
Organic Chemicals: 133
- Organometallic Compounds: 64
  - Organotechnetium Compounds: 1
    - BRU 59-21: 2

Experts

1.	Balm, Alfons J M: 1 article (09/2002)
2.	Begg, Adrian C: 1 article (09/2002)
3.	Haustermans, Karin M G: 1 article (09/2002)
4.	Hoebers, Frank J P: 1 article (09/2002)
5.	Hoefnagel, Cees A: 1 article (09/2002)
6.	Janssen, Hilde L K: 1 article (09/2002)
7.	Nunn, Adrian D: 1 article (09/2002)
8.	Olmos, A Valdés: 1 article (09/2002)
9.	Sprong, Debbie: 1 article (09/2002)
10.	Ballinger, J R: 1 article (11/2001)

Related Diseases

1.	Hypoxia (Hypoxemia) 11/01/2001 - "Both BRU59-21 and 99mTc-BnAO share properties making them suitable for hypoxia imaging." 09/01/2002 - "Phase 1 study to identify tumour hypoxia in patients with head and neck cancer using technetium-99m BRU 59-21."
2.	Head and Neck Neoplasms (Head and Neck Cancer) 09/01/2002 - "Phase 1 study to identify tumour hypoxia in patients with head and neck cancer using technetium-99m BRU 59-21." 09/01/2002 - "The aim of this study was to assess the safety and biodistribution of technetium-99m BRU 59-21, a novel radioactively labelled 2-nitro-imidazole hypoxic marker, in head and neck cancer patients and to correlate uptake with pimonidazole staining. "

Related Drugs and Biologics

1.	pimonidazole