zerumbone

01/29/2020 - "Zerumbone significantly reduced the severity of disease activity index (DAI) scores as well as several parameters of colonic inflammation (i.e., colon weight, colon length, cecum weight and spleen weight). "
01/01/2013 - "Moreover, the histological evaluation of liver specimens demonstrated that the steatosis and inflammation in liver of zerumbone-treated groups were improved. "
10/01/2010 - "Anti-inflammatory effect of zerumbone on acute and chronic inflammation models in mice."
09/27/2023 - "The aim of the current study was to determine the mechanism by which Zerumbone (ZER) ameliorates inflammation and organ damage in a rat model of severe acute pancreatitis (SAP). "
04/06/2011 - "This study aims to determine the effect of zerumbone, a potent NF-κB inhibitor and inflammation modulators, on UVB-induced corneal damages in a mouse model. "

01/01/2014 - "Furthermore, we should determine the efficacy of zerumbone by in vivo studies using proper animal models of cancer and demonstrate their safety and effectiveness in clinical trials. "
07/13/2023 - "Zerumbone (ZER) is natural compound commonly found in the roots of Zingiber zerumbet which has recently demonstrated anti-cancer activity in both in vitro and in vivo studies. "
01/01/2018 - "The current study determined the effect of zerumbone on factors associated with angiogenesis that occurs in tumor formation. "
02/01/2023 - "Zerumbone had been verified as a potential anti-cancer agent. "
09/01/2022 - "Therefore, we aimed to investigate the in vitro anti-cancer effects of the zerumbone in CRC, focusing on cell apoptosis and migration. "

08/01/2014 - "Notch2 activation is protective against anticancer effects of zerumbone in human breast cancer cells."
12/01/2014 - "In the present study, we investigated the role of zerumbone (ZER) on regulatory mechanisms of CD44 expression in breast cancer cells. "
02/01/2023 - "The prooxidant properties of zerumbone potentially resensitize breast cancer cells to PTX by enhancing intracellular ROS-mediated oxidative stress."
02/01/2023 - "Here, we evaluated the chemosensitization potential of zerumbone in a breast cancer cell line in vitro. "
09/01/2021 - "We further explored the ability of this compound compared to zerumbone in inhibiting the growth of MCF-7 breast cancer cells. "

10/09/2023 - "Zerumbone, a natural molecule, has anti-oxidative and anti-inflammatory properties that may help to prevent sepsis. "
10/09/2023 - "Our findings demonstrate that zerumbone pretreatment suppresses sepsis-induced ALI via antioxidative activities and anti-inflammatory, implying that zerumbone could be a viable preventive agent for sepsis-induced ALI."
10/09/2023 - "The obtained results revealed that zerumbone inhibited the sepsis-induced ALI through its anti-inflammatory and antioxidative activity via inhibition of the NF-κB pathway and activation of HO-1 pathway. "
10/09/2023 - "We found that zerumbone greatly decreased the sepsis-induced ALI using histological investigations. "
10/09/2023 - "In the present study, we have assessed the protective effect of zerumbone against sepsis-induced acute lung injury (ALI) and its underlying mechanisms. "

06/24/2021 - "This finding will contribute to advance our knowledge on zerumbone and its significance in treating neuropathic pain."
06/24/2021 - "Zerumbone, of the Zingiber zerumbet ginger plant, has exhibited anti-allodynic and antihyperalgesic effects in a neuropathic pain animal model, amongst other pharmacological properties. "
08/26/2020 - "Symptoms of neuropathic pain were significantly alleviated following treatment with zerumbone (10 mg/kg; intraperitoneal, i.p.). "
01/01/2020 - "Zerumbone has shown great potential in various pathophysiological models of diseases, particularly in neuropathic pain conditions. "
10/01/2016 - "The mechanism through which zerumbone alleviates neuropathic pain has yet to be elucidated. "