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nepalolide A

structure in first source

Also Known As:

nepalolide-A

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Polycyclic Aromatic Hydrocarbons: 2020
        Anthracenes: 12
        nepalolide A: 1
Polycyclic Compounds: 6
- Polycyclic Aromatic Hydrocarbons: 2020
  - Anthracenes: 12
    - nepalolide A: 1

Related Diseases

1.	Necrosis 09/01/1999 - "1 The effects of nepalolide A on the expression of inducible nitric oxide synthase (iNOS) caused by incubation with lipopolysaccharide/interferon-gamma (LPS/IFN-gamma) or tumour necrosis factor-alpha/interleukin-1beta/IFN-gamma (TNF-alpha/IL-1beta/IFN-gamma, mixed cytokines) in C6 glioma cells and primary astrocytes of rat were investigated. "
2.	Glioma (Gliomas) 09/01/1999 - "Nepalolide A at 10 microM abrogated the LPS/IFN-gamma- and mixed cytokines-mediated induction of iNOS by more than 90% in C6 glioma cells, and by 80% for mixed cytokines-induced induction of iNOS in primary astrocytes. " 09/01/1999 - "Nepalolide A inhibits the expression of inducible nitric oxide synthase by modulating the degradation of IkappaB-alpha and IkappaB-beta in C6 glioma cells and rat primary astrocytes." 09/01/1999 - "1 The effects of nepalolide A on the expression of inducible nitric oxide synthase (iNOS) caused by incubation with lipopolysaccharide/interferon-gamma (LPS/IFN-gamma) or tumour necrosis factor-alpha/interleukin-1beta/IFN-gamma (TNF-alpha/IL-1beta/IFN-gamma, mixed cytokines) in C6 glioma cells and primary astrocytes of rat were investigated. "

Related Drugs and Biologics

1.	Interleukin-1beta (Interleukin 1 beta)
2.	Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)
3.	Cytokines
4.	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
5.	Lipopolysaccharides
6.	Interferon-gamma (Interferon, gamma)
7.	Dihydrotachysterol (AT 10)
8.	NF-KappaB Inhibitor alpha