SWR 0342SA

a beta(3) adrenergic receptor agonist; structure in first source; SWR-0315NA is a non-isomeric with racemic ethylidene group and sodium salt

Also Known As:

(4-((1-(2-((2-hydroxy-3-phenoxypropyl))amino)ethyl)-1-propenyl)phenoxy)acetic acid ethanedioic acid; SWR-0315NA; SWR-0342SA

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

1.	Obesity 10/01/1999 - "These results indicated that SWR-0342SA is a selective beta3-AR agonist, and possesses potent anti-diabetic activity, and that the anti-obesity activity is inferior to the anti-diabetic activity." 10/01/1999 - "With regards to anti-obesity and anti-diabetic activities, SWR-0342SA had no effect on body weight or food intake, but slightly decreased the fat pads weight in KK-Ay mice, an animal model of obesity and non-insulin-dependent diabetes mellitus (NIDDM). " 10/01/1999 - "We investigated the beta-adrenergic receptor (AR) agonistic activities in rats and humans, and the anti-obesity and anti-diabetic activities in KK-Ay mice, of a new beta3-AR agonist, SWR-0342SA ((S)-(Z)-[4-[[1-[2-[(2-hydroxy-3-phenoxypropyl)]amino]ethyl]-1-pro penyl]phenoxy] acetic acid ethanedioic acid). "
2.	Type 2 Diabetes Mellitus (MODY) 10/01/1999 - "With regards to anti-obesity and anti-diabetic activities, SWR-0342SA had no effect on body weight or food intake, but slightly decreased the fat pads weight in KK-Ay mice, an animal model of obesity and non-insulin-dependent diabetes mellitus (NIDDM). "
3.	Body Weight (Weight, Body) 10/01/1999 - "With regards to anti-obesity and anti-diabetic activities, SWR-0342SA had no effect on body weight or food intake, but slightly decreased the fat pads weight in KK-Ay mice, an animal model of obesity and non-insulin-dependent diabetes mellitus (NIDDM). "

1.	Oxalic Acid (Disodium Oxalate)
2.	Acetic Acid (Vinegar)
3.	beta Adrenergic Receptors