HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

KIN 844

structure in first source

Also Known As:

KIN-844

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Nitro Compounds: 66
  - Nitroimidazoles: 565
    - KIN 844: 2
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Imidazoles: 150
      - Nitroimidazoles: 565
        KIN 844: 2

Experts

1.	Abou-Bedair, Farid Ahmed: 1 article (05/2002)
2.	Abu-Zeid, Medhat: 1 article (05/2002)
3.	Hori, Hitoshi: 1 article (05/2002)
4.	Inayama, Seiichi: 1 article (05/2002)
5.	Nagasawa, Hideko: 1 article (05/2002)
6.	Uto, Yoshihiro: 1 article (05/2002)

Related Diseases

1.	Neoplasms (Cancer) 11/01/1999 - "In each group, KIN-806, KIN-804, and KIN-844 markedly suppressed tumor regrowth in comparison with animals that received irradiation alone. " 11/01/1999 - "Seventeen days after inoculation of SCCVII tumor cells into the animals, 0.4 g/kg of KIN-806, KIN-804, and KIN-844 was administered to each radiosensitizer group 30 min before 40 Gy was delivered as local irradiation. "
2.	Neoplasm Metastasis (Metastasis) 11/01/1999 - "Its radiosensitizing effects and the degree of lung metastasis detected were evaluated and compared with its analogs KIN-804 and KIN-844. "
3.	Carcinoma (Carcinomatosis) 05/01/2002 - "Comparison of hypoxic cell radiosensitizers, KIN-804, KIN-844, KIN-806 and TX-1877, on brain and liver metabolizing capacities in mice bearing Ehrlich ascites carcinoma." 05/01/2002 - "The biochemical effects of the 2-nitroimidazole hypoxic cell radiosensitizers KIN-804, KIN-806, and their analogues KIN-844 and TX-1877 on brain acetylcholinesterase (AChE) and hepatic free radical scavenging systems, such as reduced glutathione (GSH) and glucose-6-phosphate dehydrogenase (G-6-PDH) levels, and hepatic antioxidants, such as superoxide dismutase (SOD) and catalase, were evaluated in Ehrlich ascites carcinoma (EAC)-bearing Swiss albino mice. "
4.	Body Weight (Weight, Body) 05/01/2002 - "To evaluate the hepatic metabolic capacity, groups of mice were divided into control, EAC-inoculated, 10-Gy local gamma-irradiated, and KIN-804, KIN-844, KIN-806, or TX-1877 (50 mg/kg body weight, i.p.) groups, and gamma-irradiation was combined with each drug. "
5.	Ascites 05/01/2002 - "Comparison of hypoxic cell radiosensitizers, KIN-804, KIN-844, KIN-806 and TX-1877, on brain and liver metabolizing capacities in mice bearing Ehrlich ascites carcinoma." 05/01/2002 - "The biochemical effects of the 2-nitroimidazole hypoxic cell radiosensitizers KIN-804, KIN-806, and their analogues KIN-844 and TX-1877 on brain acetylcholinesterase (AChE) and hepatic free radical scavenging systems, such as reduced glutathione (GSH) and glucose-6-phosphate dehydrogenase (G-6-PDH) levels, and hepatic antioxidants, such as superoxide dismutase (SOD) and catalase, were evaluated in Ehrlich ascites carcinoma (EAC)-bearing Swiss albino mice. "

Related Drugs and Biologics

1.	KIN 806
2.	2- nitroimidazole- 1- methylacetohydroxamate
3.	Superoxide Dismutase
4.	Radiation-Sensitizing Agents
5.	Glutathione (Reduced Glutathione)
6.	Glucosephosphate Dehydrogenase (Glucose 6 Phosphate Dehydrogenase)
7.	Free Radicals
8.	Catalase
9.	Antioxidants
10.	Acetylcholinesterase