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defoslimod

structure in first source

Also Known As:

OM 174; OM 174 lipid

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Related Diseases

1.	Neoplasms (Cancer) 06/01/1999 - "OM 174 was not directly toxic for tumor cells, and thus the observed effect involved the host-mediated antitumor reaction. " 06/01/1999 - "When injected 15 times intravenously, at the dose of 1 mg/kg, 2 days apart, OM 174 induced the complete regression of tumors and hemorrhagic ascitis in 90% of the tumor-bearing rats, whereas all the untreated rats died of their tumors. " 06/01/1999 - "Therefore we hypothesize that OM 174 therapy induces tumor cell apoptosis, stimulates the phagocytosis of apoptotic bodies and then activates immune system by antigen presentation."
2.	Neoplasm Metastasis (Metastasis) 06/01/1999 - "Cure of colon cancer metastasis in rats with the new lipid A OM 174. "
3.	Colonic Neoplasms (Colon Cancer) 06/01/1999 - "The antitumoral effect of the new lipid A OM 174 was investigated in a model of colon cancer in rats. " 06/01/1999 - "Cure of colon cancer metastasis in rats with the new lipid A OM 174. "

Related Drugs and Biologics

1.	Lipid A

Related Therapies and Procedures

1.	Therapeutics