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defoslimod
structure in first source
Also Known As:
OM 174; OM 174 lipid
Networked:
1
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Carbohydrates: 22023
Polysaccharides: 15383
Bacterial Polysaccharides: 50
Lipopolysaccharides: 27188
defoslimod: 1
Glycoconjugates: 1353
Lipopolysaccharides: 27188
defoslimod: 1
Lipids: 114793
Lipopolysaccharides: 27188
defoslimod: 1
Biological Factors: 2472
Antigens: 143924
Bacterial Antigens: 807
Bacterial Polysaccharides: 50
Lipopolysaccharides: 27188
defoslimod: 1
Biological Toxins: 20
Bacterial Toxins: 814
Endotoxins: 14335
Lipopolysaccharides: 27188
defoslimod: 1
Related Diseases
1.
Neoplasms (Cancer)
06/01/1999 - "
OM 174 was not directly toxic for tumor cells, and thus the observed effect involved the host-mediated antitumor reaction.
"
06/01/1999 - "
When injected 15 times intravenously, at the dose of 1 mg/kg, 2 days apart, OM 174 induced the complete regression of tumors and hemorrhagic ascitis in 90% of the tumor-bearing rats, whereas all the untreated rats died of their tumors.
"
06/01/1999 - "
Therefore we hypothesize that OM 174 therapy induces tumor cell apoptosis, stimulates the phagocytosis of apoptotic bodies and then activates immune system by antigen presentation.
"
2.
Neoplasm Metastasis (Metastasis)
06/01/1999 - "
Cure of colon cancer metastasis in rats with the new lipid A OM 174.
"
3.
Colonic Neoplasms (Colon Cancer)
06/01/1999 - "
The antitumoral effect of the new lipid A OM 174 was investigated in a model of colon cancer in rats.
"
06/01/1999 - "
Cure of colon cancer metastasis in rats with the new lipid A OM 174.
"
Related Drugs and Biologics
1.
Lipid A
Related Therapies and Procedures
1.
Therapeutics